Autophagy in major human diseases
Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
Acyl coenzyme A binding protein (ACBP): An aging‐and disease‐relevant “autophagy checkpoint”
Acyl coenzyme A binding protein (ACBP), also known as diazepam‐binding inhibitor (DBI),
is a phylogenetically ancient protein present in some eubacteria and the entire eukaryotic …
is a phylogenetically ancient protein present in some eubacteria and the entire eukaryotic …
Acyl-CoA binding protein for the experimental treatment of anorexia
Extracellular acyl-coenzyme A binding protein [ACBP encoded by diazepam binding
inhibitor (DBI)] is a phylogenetically ancient appetite stimulator that is secreted in a …
inhibitor (DBI)] is a phylogenetically ancient appetite stimulator that is secreted in a …
ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, inflammation, and fibrosis
O Motiño, F Lambertucci… - Proceedings of the …, 2022 - National Acad Sciences
Acyl-coenzyme A (CoA)–binding protein (ACBP), also known as diazepam-binding inhibitor
(DBI), is an extracellular feedback regulator of autophagy. Here, we report that injection of a …
(DBI), is an extracellular feedback regulator of autophagy. Here, we report that injection of a …
[HTML][HTML] Acyl-coenzyme a binding protein (ACBP)-a risk factor for cancer diagnosis and an inhibitor of immunosurveillance
Background The plasma concentrations of acyl coenzyme A binding protein (ACBP, also
known as diazepam-binding inhibitor, DBI, or 'endozepine') increase with age and obesity …
known as diazepam-binding inhibitor, DBI, or 'endozepine') increase with age and obesity …
Old paradoxes and new opportunities for appetite control in obesity
Human obesity is accompanied by alterations in the blood concentrations of multiple
circulating appetite regulators. Paradoxically, most of the appetite-inhibitory hormones are …
circulating appetite regulators. Paradoxically, most of the appetite-inhibitory hormones are …
High plasma concentrations of acyl‐coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging …
Autophagy defects accelerate aging, while stimulation of autophagy decelerates aging. Acyl‐
coenzyme A binding protein (ACBP), which is encoded by a diazepam‐binding inhibitor …
coenzyme A binding protein (ACBP), which is encoded by a diazepam‐binding inhibitor …
Synthesis of novel MOF-on-MOF composite as a magnetic sorbent to dispersive micro solid phase extraction of benzodiazepine drugs prior to determination with …
MOK Abad, M Masrournia, A Javid - Microchemical Journal, 2024 - Elsevier
Diazepam and lorazepam are two benzodiazepine drugs widely prescribed as
antidepressants and antiepileptics. A straightforward and time-save dispersive micro solid …
antidepressants and antiepileptics. A straightforward and time-save dispersive micro solid …
From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI
Four decades ago Costa and colleagues identified a small, secreted polypeptide in the brain
that can displace the benzodiazepine diazepam from the GABA A receptor, and was thus …
that can displace the benzodiazepine diazepam from the GABA A receptor, and was thus …
[HTML][HTML] The missing hallmark of health: psychosocial adaptation
C López-Otín, G Kroemer - Cell Stress, 2024 - ncbi.nlm.nih.gov
The eight biological hallmarks of health that we initially postulated (Cell. 2021 Jan 7; 184 (1):
33-63) include features of spatial compartmentalization (integrity of barriers, containment of …
33-63) include features of spatial compartmentalization (integrity of barriers, containment of …