The hand endows us with unparalleled precision and versatility in our interactions with
objects, from mundane activities such as grasping to extraordinary ones such as virtuoso …

A spinal cord injury disrupts communication between the brain and the circuits in the spinal
cord that regulate neurological functions. The consequences are permanent paralysis, loss …

Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

The effects of autonomic innervation of tumors on tumor growth remain unclear. Here we
developed a series of genetic techniques to manipulate autonomic innervation in a tumor …

Deciphering how neural circuits are anatomically organized with regard to input and output
is instrumental in understanding how the brain processes information. For example, locus …

The tetracycline-controlled Tet-Off and Tet-On gene expression systems are used to regulate
the activity of genes in eukaryotic cells in diverse settings, varying from basic biological …

Severe spinal cord contusions interrupt nearly all brain projections to lumbar circuits
producing leg movement. Failure of these projections to reorganize leads to permanent …

Many human spinal cord injuries are anatomically incomplete but exhibit complete paralysis.
It is unknown why spared axons fail to mediate functional recovery in these cases. To …

Our understanding of the functions of motor system evolved remarkably in the last 20 years.
This is the consequence not only of an increase in the amount of data on this system but …

Current models of somatosensory perception emphasize transmission from primary sensory
neurons to the spinal cord and on to the brain,,–. Mental influence on perception is largely …