Melatonin is an important endogenous hormone that modulates homeostasis in the
microenvironment. Recent studies have indicated that serum melatonin levels are closely …

Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the
work of the superior biological clock and consequently affects many processes in the human …

Ongoing research has highlighted the significance of the cross-play of macrophages and
mesenchymal stem cells (MSCs). Lysine-specific demethylase 6B (KDM6B) has been …

The oral and maxillofacial organs play vital roles in chewing, maintaining facial beauty, and
speaking. Almost all physiological processes display circadian rhythms that are driven by …

Exposure to artificial light at night (LAN) can induce obesity, depressive disorder and
osteoporosis, but the pernicious effects of excessive LAN exposure on tissue structure are …

Secretory glands, responsible for tears and saliva production, play essential roles in
maintaining ocular and oral well-being. Disruptions in gland secretion can arise from various …

The occurrence of aging is intricately associated with alterations in circadian rhythms that
coincide with stem cell exhaustion. Nonetheless, the extent to which the circadian system …

Circadian rhythms play a crucial role in regulating various physiological processes,
including specific immune functions that enhance the body's ability to anticipate and …

Although physical training has been shown to improve bone mass, the time of day to
exercise for optimal bone growth remains uncertain. Here we show that engaging in …

Circadian rhythm is ubiquitous in nature. Circadian clock genes such as Bmal1 and Clock
form a multi-level transcription-translation feedback network, and regulate a variety of …