Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana

EA Ofori, JKA Tetteh, A Frimpong, H Ganeshan… - Malaria Journal, 2021 - Springer
Background Malaria eradication requires a combined effort involving all available control
tools, and these efforts would be complemented by an effective vaccine. The antigen targets …

Immunodominant t cell peptides from four candidate malarial antigens as biomarkers of protective immunity against malaria

M Belmonte, H Ganeshan, J Huang, A Belmonte… - Vaccine, 2023 - Elsevier
A malaria vaccine with high efficacy and capable of inducing sterile immunity against
malaria within genetically diverse populations is urgently needed to complement ongoing …

Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria

ON Nlinwe, EA Ofori, K Akyea-Mensah, E Kyei-Baafour… - Plos one, 2021 - journals.plos.org
Antigen polymorphisms in essential malarial antigens are a key challenge to the design and
development of broadly effective malaria vaccines. The effect of polymorphisms on antibody …

Towards large-scale identification of HLA-restricted T cell epitopes from four vaccine candidate antigens in a malaria endemic community in Ghana

KA Kusi, EA Ofori, K Akyea-Mensah, E Kyei-Baafour… - Vaccine, 2022 - Elsevier
Sterile protection against clinical malaria has been achieved in animal models and
experimental human challenge studies involving immunization with radiation attenuated …

Characterization of human antibodies against Plasmodium falciparum circumsporozoite protein (PfCSP) epitopes

OE Oludada - 2024 - archiv.ub.uni-heidelberg.de
Plasmodium falciparum malaria, a mosquito-borne, unicellular parasitic disease, remains a
major health concern, particularly in the sub-Saharan Africa. Despite many attempts to …

Improving the Knowledge of EPM

LA Helber - 2024 - vtechworks.lib.vt.edu
Equine protozoal Myeloencephalitis (EPM) is a neurologic disease in horses predominantly
caused by the protozoa Sarcocystis neurona. Carried by the North American opossum …

Caracterização da resposta imune celular e humoral frente ao antígeno protetor rico em cisteína de p. Vivax (pvcyrpa) em indivíduos da amazônia brasileira

IF Soares - 2021 - arca.fiocruz.br
As infecções causadas por Plasmodium vivax representam um grave problema de saúde
pública, sendo esta espécie plasmodial considerada uma das mais difíceis de se eliminar …