Background Community-based active case-finding interventions might identify and treat
more people with tuberculosis disease than standard case detection. We aimed to assess …

Latent tuberculosis infection was the term traditionally used to indicate tuberculosis (TB)
infection. This term was used to define “a state of persistent immune response to stimulation …

The current dogma is that 2 billion individuals, making up a quarter of the world's population,
are latently infected with Mycobacterium tuberculosis (1–4). It is thought that latent …

From Chlamydia (1) to malaria (2) to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)(3), it is increasingly recognized that individuals without recognizable …

Background Targeted preventive therapy for individuals at highest risk of incident
tuberculosis might impact the epidemic by interrupting transmission. We tested performance …

Tuberculosis (TB) is a leading cause of morbidity and mortality from a single infectious
agent, despite being preventable and curable. Early and accurate diagnosis of active TB is …

There have been few independent evaluations of computer-aided detection (CAD) software
for tuberculosis (TB) screening, despite the rapidly expanding array of available CAD …

Great progress has been made over the past half-century, but TB remains a formidable
global health problem, particularly in low-and middle-income countries. Understanding the …

Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Background Tuberculosis remains an important clinical and public health issue in South
Africa, which has one of the highest tuberculosis burdens in the world. We aimed to estimate …