Coenzyme Q (CoQ) is present in all cells and membranes and in addition to be a member of
the mitochondrial respiratory chain it has also several other functions of great importance for …

Mitochondria are deeply involved in the production of reactive oxygen species through one-
electron carriers in the respiratory chain; mitochondrial structures are also very susceptible …

Alzheimer's disease (AD) includes etiologically heterogenous disorders characterized by
senile or presenile dementia, extracellular amyloid protein aggregations containing an …

The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS),
considered as the pathogenic agent of many diseases and of aging. We have investigated …

The clinical experience in cardiology with CoQ [TeX:] _ {10} includes studies on congestive
heart failure, ischemic heart disease, hypertensive heart disease, diastolic dysfunction of the …

In both humans and animals there is a progressive loss of muscle strength with age. Tests of
handgrip and knee extension in men show that some decline in strength is evident by the …

Recently, we proposed a hypothetical model of coexistence of “Reactive oxygen cycle” with
Q cycle and H+ cycle in mitochondrial respiratory chain to combine both processes of …

Mitochondria are strongly involved in the production of reactive oxygen species, considered
as the pathogenic agent of many diseases and of aging. The mitochondrial theory of aging …

In this review we summarise the current state of knowledge of the therapeutic efficacy and
mechanisms of action of CoQ10 in cardiovascular disease. Our conclusions are: 1. There is …

The depletion of the essential nutrient CoQ10 by the increasingly popular cholesterol
lowering drugs, HMG CoA reductase inhibitors (statins), has grown from a level of concern to …