Zoonotic hepatitis E virus: classification, animal reservoirs and transmission routes

V Doceul, E Bagdassarian, A Demange, N Pavio - Viruses, 2016 - mdpi.com
During the past ten years, several new hepatitis E viruses (HEVs) have been identified in
various animal species. In parallel, the number of reports of autochthonous hepatitis E in …

Expanding host range and cross-species infection of hepatitis E virus

XJ Meng - PLoS pathogens, 2016 - journals.plos.org
Hepatitis E is an important public health disease [1]. Although the mortality rate is less than
1% in the general population, it can reach up to 25% in infected pregnant women. According …

Molecular biology and infection of hepatitis E virus

Y Nan, YJ Zhang - Frontiers in microbiology, 2016 - frontiersin.org
Hepatitis E virus (HEV) is a viral pathogen transmitted primarily via fecal-oral route. In
humans, HEV mainly causes acute hepatitis and is responsible for large outbreaks of …

Zoonotic hepatitis E virus: an ignored risk for public health

Y Nan, C Wu, Q Zhao, EM Zhou - Frontiers in microbiology, 2017 - frontiersin.org
Hepatitis E virus (HEV) is a quasi-enveloped, single-stranded positive-sense RNA virus.
HEV belongs to the family Hepeviridae, a family comprised of highly diverse viruses …

Mechanism of cross-species transmission, adaptive evolution and pathogenesis of hepatitis E virus

PP Primadharsini, S Nagashima, H Okamoto - Viruses, 2021 - mdpi.com
Hepatitis E virus (HEV) is the leading cause of acute hepatitis worldwide. While the
transmission in developing countries is dominated by fecal-oral route via drinking …

Positive regulation of hepatitis E virus replication by microRNA-122

B Haldipur, PL Bhukya, V Arankalle, K Lole - Journal of virology, 2018 - Am Soc Microbiol
The molecular mechanisms of liver pathology and clinical disease in hepatitis E virus (HEV)
infection remain unclear. MicroRNAs (miRNAs) are known to modulate viral pathogenesis …

Development and characterization of efficient cell culture systems for genotype 1 hepatitis E virus and its infectious cDNA clone

PP Primadharsini, S Nagashima, T Tanaka, S Jirintai… - Viruses, 2023 - mdpi.com
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis globally. Genotype 1 HEV
(HEV-1) is responsible for multiple outbreaks in developing countries, causing high mortality …

The hepatitis E virus open reading frame 2 protein: beyond viral capsid

Z Zhou, Y Xie, C Wu, Y Nan - Frontiers in Microbiology, 2021 - frontiersin.org
Hepatitis E virus (HEV) is a zoonotic pathogen causing hepatitis in both human and animal
hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of …

Hepatitis E virus: an emerging foodborne pathogen

LC Harrison, E DiCaprio - Frontiers in Sustainable Food Systems, 2018 - frontiersin.org
Hepatitis E Virus (HEV) is endemic in areas with poor sanitation and has traditionally been
classified as a water-borne virus. Until recently, cases of HEV in industrialized countries …

Avian hepatitis E virus: with the trend of genotypes and host expansion

P Sun, S Lin, S He, EM Zhou, Q Zhao - Frontiers in Microbiology, 2019 - frontiersin.org
Avian hepatitis E virus (HEV) is a single-stranded, positive-sense RNA virus with a complete
genome of approximately 6.6 kb in size. To date, four major genotypes of avian HEV have …