There is no greater trauma than a large burn. No single injury affects more organ systems
than a severe burn injury. The subsequent supraphysiologic responses to that injury lead to …

Background Smoke inhalation injury increases overall burn mortality by up to 20 times.
Current therapy remains supportive with a failure to identify an optimal or targeted treatment …

This study tested the hypothesis that both allogenic adipose-derived mesenchymal stem
cells (ADMSCs) and human inducible pluripotent stem cell-derived MSCs (iPS-MSCs) …

Background: Smoke inhalation–associated acute lung injury (SI-ALI) is a major cause of
morbidity and mortality in victims of fire tragedies. To date, there are no evidence-based …

Background The use of hydroxocobalamin has long been advocated for treating suspected
cyanide poisoning after smoke inhalation. Intravenous hydroxocobalamin has however …

Smoke inhalation causes acute lung injury (ALI), a severe clinical disease with high
mortality. Accumulating evidence indicates that microRNA-155 (miR-155) and suppressor of …

Smoke inhalation leads to acute lung injury (ALI), a devastating clinical problem associated
with high mortality rates. Suppressor of cytokine signaling-1 (SOCS-1) is a negative …

Introduction Inhalation injuries carry significant acute care burden including prolonged
ventilator days and length of stay. However, few studies have examined post-acute …

Background: Burn injuries with≥ 70% total body surface area (TBSA) are especially acute
and life-threatening, leading to severe complications and terrible prognosis, while a …

Inhalation injuries arising from exposure to toxic gases or smoke in fires or industrial
accidents pose grave risks and significant respiratory complications. The limited efficacy of …