To evaluate the efficiency of pan-keratin immunostaining, tissue microarrays of 13,501 tumor
samples from 121 different tumor types and subtypes as well as 608 samples of 76 different …

Background Pathologists commonly employ the Ki67 immunohistochemistry labelling index
(LI) when deciding appropriate therapeutic strategies for patients with breast cancer …

Breast cancer is a heterogeneous and dynamic disease, in which cancer cells are highly
responsive to alterations in the microenvironment. Today, conventional methods of detecting …

Survival and life quality of breast cancer patients could be improved by more aggressive
chemotherapy for those at high metastasis risk and less intense treatments for low-risk …

To reveal the best choice of algorithm for parvalbumin-immunostained images of the
hippocampal gyrus dentatus in two distinct rat models of Parkinson's disease (PD) …

Introduction Mechanical forces provide critical biological signals to cells. Within the distal
lung, tensile forces act across the basement membrane and epithelial cells atop. Stretching …

Small cell lung cancer (SCLC) is an aggressive neuroendocrine disease with an overall 5
year survival rate of~ 7%. Although patients tend to respond initially to therapy, therapy …

Background: Owing to the restricted predictive value of conventional prognostic factors and
the inconsistent treatment strategies, several oral squamous cell carcinoma (OSCC) patients …

Cancer risk prognosis could improve patient survival through early personalized treatment
decisions. This is the first systematic analysis of the spatial and prognostic distribution of …

An 11-year-old male common marmoset (Callithrix jacchus) presented with chronic,
progressive weight loss and diarrhoea. Response to treatment with nutritional …