Factors that influence the immune response to vaccination

P Zimmermann, N Curtis - Clinical microbiology reviews, 2019 - Am Soc Microbiol
There is substantial variation between individuals in the immune response to vaccination. In
this review, we provide an overview of the plethora of studies that have investigated factors …

The influence of the intestinal microbiome on vaccine responses

P Zimmermann, N Curtis - Vaccine, 2018 - Elsevier
There is substantial variation between individuals in the immune response to vaccinations.
The intestinal microbiome plays a crucial rule in the development and regulation of the …

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

N Hernandez, G Bucciol, L Moens, J Le Pen… - Journal of Experimental …, 2019 - rupress.org
Vaccination against measles, mumps, and rubella (MMR) and yellow fever (YF) with live
attenuated viruses can rarely cause life-threatening disease. Severe illness by MMR …

Role of multivalency and antigenic threshold in generating protective antibody responses

MK Slifka, IJ Amanna - Frontiers in immunology, 2019 - frontiersin.org
Vaccines play a vital role in protecting our communities against infectious disease.
Unfortunately, some vaccines provide only partial protection or in some cases vaccine …

The influence of probiotics on vaccine responses–a systematic review

P Zimmermann, N Curtis - Vaccine, 2018 - Elsevier
The immunomodulatory effects of probiotics may influence the response to vaccines. We
systematically reviewed prospective randomised placebo-controlled studies in humans that …

The early-life gut microbiome and vaccine efficacy

A Jordan, SR Carding, LJ Hall - The Lancet Microbe, 2022 - thelancet.com
Vaccines are one of the greatest successes of public health, preventing millions of cases of
disease and death in children each year. However, the efficacy of many vaccines can vary …

The double-edged sword: How evolution can make or break a live-attenuated virus vaccine

KA Hanley - Evolution: Education and Outreach, 2011 - Springer
Even students who reject evolution are often willing to consider cases in which evolutionary
biology contributes to, or undermines, biomedical interventions. Moreover, the intersection of …

Immunogenicity and safety of concomitant and sequential administration of yellow fever YF-17D vaccine and tetravalent dengue vaccine candidate TAK-003: A phase …

V Tricou, B Essink, JE Ervin, M Turner… - PLOS Neglected …, 2023 - journals.plos.org
Background Yellow fever (YF) vaccination is often mandatory for travelers to YF-endemic
areas. The areas with risk of YF partially overlap with those of dengue, for which there is …

17DD yellow fever vaccine: a double blind, randomized clinical trial of immunogenicity and safety on a dose-response study

RM Martins, MLS Maia, RHG Farias… - Human vaccines & …, 2013 - Taylor & Francis
Objective: To verify if the Bio-Manguinhos 17DD yellow fever vaccine (17DD-YFV) used in
lower doses is as immunogenic and safe as the current formulation. Results: Doses from …

Outflanking immunodominance to target subdominant broadly neutralizing epitopes

D Angeletti, I Kosik, JJS Santos… - Proceedings of the …, 2019 - National Acad Sciences
A major obstacle to vaccination against antigenically variable viruses is skewing of antibody
responses to variable immunodominant epitopes. For influenza virus hemagglutinin (HA) …