Achieving lysozyme functionalization in PDADMAC–NaPSS saloplastics through salt annealing

J Li, L Li, S Lindhoud - RSC advances, 2024 - pubs.rsc.org
Hot-pressed saloplastics are dense and transparent polyelectrolyte complex materials
governed by ionic crosslinking. Such plastics have several advantages, for example, salt …

pH-dependent interactions of biologically important metal ions with hen egg white lysozyme based on its hydration properties: Thermodynamic and mechanistic …

A Maheshwari, N Kishore - International Journal of Biological …, 2024 - Elsevier
Importance of metal ion selectivity in biomolecules and their key role in proteins are widely
explored. However, understanding the thermodynamics of how hydrated metal ions alter the …

Thermodynamic origin of differential excipient-lysozyme interactions

J Kalayan, RA Curtis, J Warwicker… - Frontiers in Molecular …, 2021 - frontiersin.org
Understanding the intricate interplay of interactions between proteins, excipients, ions and
water is important to achieve the effective purification and stable formulation of protein …

Ion-specificity in protein binding and recovery for the responsive hydrophobic poly (vinylcaprolactam) ligand

Z Liu, SR Wickramasinghe, X Qian - RSC advances, 2017 - pubs.rsc.org
The conformational switch between the hydrophobic state and hydrophilic state of thermo-
responsive poly (vinylcaprolactam)(PVCL) has great potential for protein binding and elution …

Correlating multidimensional short-term empirical protein properties to long-term protein physical stability data via empirical phase diagrams

ME Klijn, J Hubbuch - International Journal of Pharmaceutics, 2019 - Elsevier
Identification of long-term stable biopharmaceutical formulations is essential for
biopharmaceutical product development. Reduction of the number of long-term storage …

[PDF][PDF] H+ 对溶菌酶热变性过程的促进机制

李梦娜 - 中国科学技术大学学报, 2020 - just.ustc.edu.cn
利用自发拉曼光谱方法研究了H+ 在溶菌酶热变性过程中对其起始变性温度的影响, 分析了H+
在溶菌酶变性过程中与其分子上氨基酸残基相互作用的动力学过程. 在变性过程中同步记录并 …

[图书][B] Computational Studies of Protein-Excipient Interactions-Thermodynamic Theory Development and Application to Solutions

J Kalayan - 2021 - search.proquest.com
With advances in technology, biopharmaceuticals are increasingly used to treat a wide
range of diseases, with particular advantages in targetted and tailored treatment compared …

The kinetic mechanism of H+ in lysozyme with increasing temperature

LI Mengna - JUSTC, 2020 - just.ustc.edu.cn
In this study, Raman spectroscopy was employed to study the kinetic mechanism of
lysozyme denaturation at high temperatures induced by Abstract In this study, Raman …

[PDF][PDF] Working experience

EJ Guo - EPS, 2021 - people.earth.yale.edu
Meng Guo Education Working Experience Page 1 Meng Guo Department of Earth and
Planetary Sciences, Yale University Tel: (240)413-5622 | meng.guo@yale.edu | Meng …

[PDF][PDF] Computational methods for long-term protein phase behavior analysis

M Klijn - 2019 - core.ac.uk
The work presented in this thesis contributes to long-term protein phase behavior research.
Long-term protein phase behavior plays a pivotal role in biotechnological product and …