RNA structural dynamics as captured by molecular simulations: a comprehensive overview
With both catalytic and genetic functions, ribonucleic acid (RNA) is perhaps the most
pluripotent chemical species in molecular biology, and its functions are intimately linked to …
pluripotent chemical species in molecular biology, and its functions are intimately linked to …
[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis
M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
Advancement of the emerging field of RNA nanotechnology
The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
[PDF][PDF] Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions
A Brown, F Long, RA Nicholls, J Toots… - … Section D: Biological …, 2015 - journals.iucr.org
The recent rapid development of single-particle electron cryo-microscopy (cryo-EM) now
allows structures to be solved by this method at resolutions close to 3 Å. Here, a number of …
allows structures to be solved by this method at resolutions close to 3 Å. Here, a number of …
A deep learning framework for modeling structural features of RNA-binding protein targets
RNA-binding proteins (RBPs) play important roles in the post-transcriptional control of
RNAs. Identifying RBP binding sites and characterizing RBP binding preferences are key …
RNAs. Identifying RBP binding sites and characterizing RBP binding preferences are key …
Profiling of 2′-O-Me in human rRNA reveals a subset of fractionally modified positions and provides evidence for ribosome heterogeneity
Ribose methylation is one of the two most abundant modifications in human ribosomal RNA
and is believed to be important for ribosome biogenesis, mRNA selectivity and translational …
and is believed to be important for ribosome biogenesis, mRNA selectivity and translational …
Protein–RNA interaction prediction with deep learning: structure matters
Protein–RNA interactions are of vital importance to a variety of cellular activities. Both
experimental and computational techniques have been developed to study the interactions …
experimental and computational techniques have been developed to study the interactions …
Thermostability, tunability, and tenacity of RNA as rubbery anionic polymeric materials in nanotechnology and nanomedicine—specific cancer targeting with …
RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures,
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) …
The Nucleic Acid Database: new features and capabilities
B Coimbatore Narayanan, J Westbrook… - Nucleic acids …, 2014 - academic.oup.com
Abstract The Nucleic Acid Database (NDB)(http://ndbserver. rutgers. edu) is a web portal
providing access to information about 3D nucleic acid structures and their complexes. In …
providing access to information about 3D nucleic acid structures and their complexes. In …
De novo 3D models of SARS-CoV-2 RNA elements from consensus experimental secondary structures
R Rangan, AM Watkins, J Chacon… - Nucleic acids …, 2021 - academic.oup.com
The rapid spread of COVID-19 is motivating development of antivirals targeting conserved
SARS-CoV-2 molecular machinery. The SARS-CoV-2 genome includes conserved RNA …
SARS-CoV-2 molecular machinery. The SARS-CoV-2 genome includes conserved RNA …