Molecular and tissue alterations of collagens in fibrosis

S Ricard-Blum, G Baffet, N Théret - Matrix Biology, 2018 - Elsevier
The collagen network is altered in fibrotic diseases associated with extracellular matrix
(ECM) biosynthesis and remodeling. This mini-review focuses on the quantitative and …

Quantification of collagen fiber properties in alcoholic liver fibrosis using polarization-resolved second harmonic generation microscopy

S Matsuzaki, E Hase, H Takanari, Y Hayashi… - Scientific Reports, 2023 - nature.com
Liver fibrosis is assessed mainly by conventional staining or second harmonic generation
(SHG) microscopy, which can only provide collagen content in fibrotic area. We propose to …

PSHG-TISS: A collection of polarization-resolved second harmonic generation microscopy images of fixed tissues

R Hristu, SG Stanciu, A Dumitru, LG Eftimie, B Paun… - Scientific Data, 2022 - nature.com
Second harmonic generation (SHG) microscopy is acknowledged as an established
imaging technique capable to provide information on the collagen architecture in tissues that …

Determination of extracellular matrix collagen fibril architectures and pathological remodeling by polarization dependent second harmonic microscopy

D Rouède, E Schaub, JJ Bellanger, F Ezan… - Scientific reports, 2017 - nature.com
Polarization dependence second harmonic generation (P-SHG) microscopy is gaining
increase popularity for in situ quantification of fibrillar protein architectures. In this report, we …

Analyzing the feasibility of discriminating between collagen types I and II using polarization‐resolved second harmonic generation

EI Romijn, A Finnøy, MB Lilledahl - Journal of biophotonics, 2019 - Wiley Online Library
According to previous studies, the nonlinear susceptibility tensor ratio χ33/χ31 obtained from
polarization‐resolved second harmonic generation (P‐SHG) under the assumption of …

Wavy nature of collagen fibrils deduced from the dispersion of their second-order nonlinear optical anisotropy parameters ρ

D Rouède, E Schaub, JJ Bellanger, F Ezan, F Tiaho - Optics Express, 2020 - opg.optica.org
From P-SHG experiments, second-order nonlinear optical anisotropy parameters ρ=
χ_ZZZ/χ_ZXX of collagen tissues are calculated assuming the same model of supercoiled …

Polarization-resolved SHG microscopy for biomedical applications

R Cisek, MA Harvey, E Bennett, H Jeon… - … Polarimetric Modalities for …, 2023 - Springer
Polarization-resolved second harmonic generation (PSHG) microscopy is a powerful
technique capable of differentiating biological tissues as well as determining ultrastructural …

Automated calibration and control for polarization-resolved second harmonic generation on commercial microscopes

EI Romijn, A Finnøy, R Kumar, MB Lilledahl - PloS one, 2018 - journals.plos.org
Polarization-resolved second harmonic generation (P-SHG) microscopy has evolved as a
promising technique to reveal subresolution information about the structure and orientation …

Functional second harmonic generation microscopy probes molecular dynamics with high temporal resolution

M Förderer, T Georgiev, M Mosqueira… - Biomedical optics …, 2016 - opg.optica.org
Second harmonic generation (SHG) microscopy is a powerful tool for label free ex vivo or in
vivo imaging, widely used to investigate structure and organization of endogenous SHG …

Strategies for optimizing the determination of second-order nonlinear susceptibility tensor coefficients for collagen in histological samples

B Paun, R Hristu, SG Stanciu, AV Dumitru… - IEEE …, 2019 - ieeexplore.ieee.org
Quantitative second harmonic generation microscopy methods that provide an estimate for
the molecular structure of collagen in tissues by fitting theoretical models with experimental …