Antibiotics have played a crucial role in the reduction in the incidence of TB globally as
evidenced by the fact that before the mid-20th century, the mortality rate within five years of …

Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

Tuberculosis (TB) remains one of the deadliest infectious diseases in the world and every 20
seconds a person dies from TB. An important attribute of human TB is induction of a …

Mycobacterium tuberculosis (Mtb) infection, including active tuberculosis (TB) and latent Mtb
infection (LTBI), leads to diverse outcomes owing to different host immune responses …

Lung cancer and pulmonary tuberculosis are two significant public health problems that
continue to take millions of lives each year. They may have similar symptoms and, in some …

TNF, a pleiotropic proinflammatory cytokine, is important for protective immunity and
immunopathology during Mycobacterium tuberculosis (Mtb) infection, which causes …

Tuberculosis (TB) remains a significant global health challenge, claiming the lives of up to
1.5 million individuals annually. TB is caused by the human pathogen Mycobacterium …

Tuberculosis (TB) remains the leading cause of deaths among infectious diseases
worldwide. Cutaneous Tuberculosis (CTB), caused by Mycobacterium tuberculosis (Mtb) …

Infections are known to cause tumours though more attributed to viruses. Strong
epidemiological links suggest association between bacterial infections and cancers as …

Multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) poses significant challenges to
global tuberculosis (TB) control efforts. Host-directed therapies (HDTs) offer a novel …