Defensive symbioses of animals with prokaryotic and eukaryotic microorganisms

LV Flórez, PHW Biedermann, T Engl… - Natural Product …, 2015 - pubs.rsc.org
Covering: through 2014 Many organisms team up with microbes for defense against
predators, parasites, parasitoids, or pathogens. Here we review the described protective …

Marine natural products from tunicates and their associated microbes

C Ramesh, BR Tulasi, M Raju, N Thakur, L Dufossé - Marine drugs, 2021 - mdpi.com
Marine tunicates are identified as a potential source of marine natural products (MNPs),
demonstrating a wide range of biological properties, like antimicrobial and anticancer …

Ascidians: producers of amino acid-derived metabolites

BS Davidson - Chemical reviews, 1993 - ACS Publications
During the past 25 years, marinenatural products chemists have enjoyed unrivaled success
in the discovery of unique, new compounds. History has now proven that marine organisms …

An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles

LV Flórez, K Scherlach, IJ Miller, A Rodrigues… - Nature …, 2018 - nature.com
Microbial symbionts are often a source of chemical novelty and can contribute to host
defense against antagonists. However, the ecological relevance of chemical mediators …

Exploration of acute toxicity, analgesic, anti-inflammatory, and anti-pyretic activities of the black tunicate, Phallusia nigra (Savigny, 1816) using mice model

MH Syed, A Gnanakkan, S Pitchiah - Environmental Science and Pollution …, 2021 - Springer
Among marine animals, ascidians represent the most highly evolved group for marine
natural products having rich source of bioactive secondary metabolites with promising …

Biomedical potential of marine natural products

CM Ireland, BR Copp, MP Foster, LA McDonald… - … and bioactive natural …, 1993 - Springer
Marine natural products, the secondary or nonprimary metabolites produced by organisms
that live in the sea, have received increasing attention from chemists and pharmacologists …

Discovery of a lagriamide polyketide by integrated genome mining, isotopic labeling, and untargeted metabolomics

CH Fergusson, J Saulog, BS Paulo, DM Wilson… - Chemical …, 2024 - pubs.rsc.org
Microorganisms from the order Burkholderiales have been the source of a number of
important classes of natural products in recent years. For example, study of the beetle …

From seabed to bedside: A review on promising marine anticancer compounds

E Wang, MA Sorolla, PD Gopal Krishnan, A Sorolla - Biomolecules, 2020 - mdpi.com
The marine environment represents an outstanding source of antitumoral compounds and,
at the same time, remains highly unexplored. Organisms living in the sea synthesize a wide …

Origin and variation of tunicate secondary metabolites

EW Schmidt, MS Donia, JA McIntosh… - Journal of natural …, 2012 - ACS Publications
Ascidians (tunicates) are rich sources of structurally elegant, pharmaceutically potent
secondary metabolites and, more recently, potential biofuels. It has been demonstrated that …

Thiazole: a privileged motif in marine natural products

S Kumar, R Aggarwal - Mini-Reviews in Organic Chemistry, 2019 - ingentaconnect.com
Marine natural products have proven to be a rich source of drugs and drug leads. These
natural products are secondary metabolites and show biological activity against bacteria …