Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Luteolin as a modulator of skin aging and inflammation

F Gendrisch, PR Esser, CM Schempp, U Wölfle - Biofactors, 2021 - Wiley Online Library
Luteolin belongs to the group of flavonoids and can be found in flowers, herbs, vegetables
and spices. It plays an important role in defending plants, for example against UV radiation …

Mast cells as sources of cytokines, chemokines, and growth factors

K Mukai, M Tsai, H Saito, SJ Galli - Immunological reviews, 2018 - Wiley Online Library
Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

Mast cells in inflammation and disease: recent progress and ongoing concerns

SJ Galli, N Gaudenzio, M Tsai - Annual review of immunology, 2020 - annualreviews.org
Mast cells have existed long before the development of adaptive immunity, although they
have been given different names. Thus, in the marine urochordate Styela plicata, they have …

Avermectin derivatives, pharmacokinetics, therapeutic and toxic dosages, mechanism of action, and their biological effects

G El-Saber Batiha, A Alqahtani, OB Ilesanmi, AA Saati… - Pharmaceuticals, 2020 - mdpi.com
Avermectins are a group of drugs that occurs naturally as a product of fermenting
Streptomyces avermitilis, an actinomycetes, isolated from the soil. Eight different structures …

The role of myeloid cells in cancer therapies

C Engblom, C Pfirschke, MJ Pittet - Nature Reviews Cancer, 2016 - nature.com
Recent clinical trials have demonstrated the ability to durably control cancer in some
patients by manipulating T lymphocytes. These immunotherapies are revolutionizing cancer …

Mast cell biology at molecular level: a comprehensive review

D Elieh Ali Komi, S Wöhrl, L Bielory - Clinical reviews in allergy & …, 2020 - Springer
Mast cells (MCs) are portions of the innate and adaptive immune system derived from bone
marrow (BM) progenitors that are rich in cytoplasmic granules. MC maturation, phenotype …

Mast cell secretory granules: armed for battle

S Wernersson, G Pejler - Nature Reviews Immunology, 2014 - nature.com
Mast cells are important effector cells of the immune system and recent studies show that
they have immunomodulatory roles in diverse processes in both health and disease. Mast …

Mast cell function: a new vision of an old cell

EZM da Silva, MC Jamur… - Journal of Histochemistry …, 2014 - journals.sagepub.com
Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as
effectors of allergy. It has been only in the past two decades that mast cells have gained …

Translational selenium nanoparticles to attenuate allergic dermatitis through Nrf2-Keap1-driven activation of selenoproteins

B Xie, D Zeng, M Yang, Z Tang, L He, T Chen - ACS nano, 2023 - ACS Publications
Easy recurrence and strong treatment side effects significantly limit the clinical treatment of
allergic dermatitis. The human trace element selenium (Se) plays essential roles in redox …