ACE2 interaction networks in COVID-19: a physiological framework for prediction of outcome in patients with cardiovascular risk factors

Z Wicik, C Eyileten, D Jakubik, SN Simões… - Journal of clinical …, 2020 - mdpi.com
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
(coronavirus disease 2019; COVID-19) is associated with adverse outcomes in patients with …

Improved biomarker discovery through a plot twist in transcriptomic data analysis

N Sánchez-Baizán, L Ribas, F Piferrer - BMC biology, 2022 - Springer
Background Transcriptomic analysis is crucial for understanding the functional elements of
the genome, with the classic method consisting of screening transcriptomics datasets for …

Identification of potential biomarkers and their correlation with immune infiltration cells in schizophrenia using combinative bioinformatics strategy

Z Li, X Li, M Jin, Y Liu, Y He, N Jia, X Cui, Y Liu, G Hu… - Psychiatry …, 2022 - Elsevier
Many studies have identified changes in gene expression in brains of schizophrenia
patients and their altered molecular processes, but the findings in different datasets were …

MiR-574-5P, miR-1827, and miR-4429 as potential biomarkers for schizophrenia

O Davarinejad, S Najafi, H Zhaleh… - Journal of Molecular …, 2022 - Springer
Schizophrenia is a severe chronic debilitating disorder with millions of affected individuals.
Diagnosis is based on clinical presentations, which are made when the progressive disease …

Identifying RBM47, HCK, CD53, TYROBP, and HAVCR2 as hub genes in advanced atherosclerotic plaques by network-based analysis and validation

C Liu, H Zhang, Y Chen, S Wang, Z Chen, Z Liu… - Frontiers in …, 2021 - frontiersin.org
Background: Atherosclerotic cardiovascular diseases accounted for a quarter of global
deaths. Most of these fatal diseases like coronary atherosclerotic disease (CAD) and stroke …

Coexpression modules constructed identifies regulation pathways of winter jujube (Ziziphus jujuba Mill.'Dongzao') following postharvest treatment with ozone

X Huang, Y Tian, J Xing, Y Chong, C Chen… - Postharvest Biology and …, 2023 - Elsevier
Abstract Winter jujube (Ziziphus jujuba Mill.'Dongzao') is a member of the Rhamnaceae
family known for its favorable nutritional and flavor profile. It has been considered a unique …

Integrated WGCNA and PPI network to screen hub genes signatures for infantile hemangioma

M Xu, T Ouyang, K Lv, X Ma - Frontiers in genetics, 2021 - frontiersin.org
Background Infantile hemangioma (IH) is characterized by proliferation and regression.
Methods Based on the GSE127487 dataset, the differentially expressed genes (DEGs) …

Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere …

Z Wu, E Hai, Z Di, R Ma, F Shang, Y Wang, M Wang… - PLoS …, 2020 - journals.plos.org
Objective Mature hair follicles represent an important stage of hair follicle development,
which determines the stability of hair follicle structure and its ability to enter the hair cycle …

WGCNA reveals key gene modules regulated by the combined treatment of colon cancer with PHY906 and CPT11

S Xing, Y Wang, K Hu, F Wang, T Sun, Q Li - Bioscience reports, 2020 - portlandpress.com
Irinotecan (CPT11) is one of the most effective drugs for treating colon cancer, but its severe
side effects limit its application. Recently, a traditional Chinese herbal preparation, named …

The influence of pyroptosis-related genes on the development of chronic obstructive pulmonary disease

X Liu, X Huang, F Xu - BMC Pulmonary Medicine, 2023 - Springer
Increasing evidences have demonstrated that pyroptosis exerts key roles in the occurrence,
development of chronic obstructive pulmonary disease. However, the mechanisms of …