After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Hypoxia is a common feature of the tumor microenvironment, which is characterized by
tissue oxygen deficiency due to an aggressive proliferation of cancer cells. Hypoxia …

Encapsulation of biomolecules using metal–organic frameworks (MOFs) to form stable
biocomposites has been demonstrated to be a valuable strategy for their preservation and …

In the last two decades, DNA has attracted significant attention toward the development of
materials at the nanoscale for emerging applications due to the unparalleled versatility and …

Abstract Cu doped CeO 2 (Cu-CeO 2) nanoparticles were synthesized via the hydrothermal
method, exhibiting multiple nanozyme activities such as good oxidase-like (OXD) …

Cisplatin is the most commonly used first-line drug for cancer treatment. However, many
patients develop resistance to cisplatin therapy which ultimately results in therapy failure …

Background Colorectal cancer (CRC) is the second most deadly cancer worldwide, with
chemo-resistance remaining a major obstacle in CRC treatment. Notably, the imbalance of …

Hypoxia is a common feature of solid tumors that contributes to angiogenesis, invasiveness,
metastasis, altered metabolism and genomic instability. As hypoxia is a major actor in tumor …

Highlights•PFCs efficiently deliver O 2 to tumor tissues, and can alleviate hypoxia.•PFC-
based O 2 nanocarriers increase 1 O 2 lifetime, enhancing PDT/SDT, radiotherapy and …

Hypoxia is a key impediment encountered in the treatment of most solid tumors, leading to
immune escape and therapeutic resistance. Perfluorocarbons (PFCs) have a unique …