GAPDH and β-actin protein decreases with aging, making Stain-Free technology a superior loading control in Western blotting of human skeletal muscle

A Vigelsø, R Dybboe, CN Hansen… - Journal of applied …, 2015 - journals.physiology.org
Reference proteins (RP) or the total protein (TP) loaded is used to correct for uneven loading
and/or transfer in Western blotting. However, the signal sensitivity and the influence of …

Skeletal muscle mitochondrial H2O2 emission increases with immobilization and decreases after aerobic training in young and older men

M Gram, A Vigelsø, T Yokota, JW Helge… - The Journal of …, 2015 - Wiley Online Library
Key points Currently, it is not known whether impaired mitochondrial function contributes to
human ageing or whether potential impairments in mitochondrial function with age are …

Associations of aerobic fitness and maximal muscular strength with metabolites in young men

UM Kujala, JP Vaara, H Kainulainen… - JAMA Network …, 2019 - jamanetwork.com
Importance High physical fitness is associated with a reduction in risk of cardiovascular
diseases and death, but the underlying mechanisms are insufficiently understood. Objective …

[PDF][PDF] Six weeks' aerobic retraining after two weeks' immobilization restores leg lean mass and aerobic capacity but does not fully rehabilitate leg strength in young …

A Vigelsø, M Gram, C Wiuff… - Journal of …, 2015 - medicaljournalssweden.se
OBJECTIVE: To determine the effect of aerobic retraining as rehabilitation after short-term
leg immobilization on leg strength, leg work capacity, leg lean mass, leg muscle fibre type …

[HTML][HTML] Functional characteristics of young men who regularly experience feasible physical activity

IN Medvedev, ES Kachenkova… - Biomedical and …, 2022 - biomedpharmajournal.org
In the modern world, college-age youth often have various somatic dysfunctions and
pathologies. This places an additional burden on hospitals and further increases costs in the …

Separate and combined associations of physical activity and obesity with lipid-related indices in non-diabetic and diabetic patients

Y Zhang, J Yang, J Ye, Q Guo, W Wang, Y Sun… - Lipids in health and …, 2019 - Springer
Background This study evaluated the separate and combined associations of physical
activity and obesity with blood lipids in Chinese adults with and without diabetes. Methods …

The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate‐intensity exercise in human skeletal muscle

A Vigelsø, M Gram, R Dybboe… - The Journal of …, 2016 - Wiley Online Library
Key points This study aimed to provide molecular insight into the differential effects of age
and physical inactivity on the regulation of substrate metabolism during moderate‐intensity …

Maintaining a clinical weight loss after intensive lifestyle intervention is the key to cardiometabolic health

S Dandanell, C Skovborg, CB Præst… - Obesity Research & …, 2017 - Elsevier
Objective Intensive lifestyle interventions (ILI) are criticised for ineffective obesity treatment
because weight loss over time is modest and thus of limited clinical relevance. However, a …

[PDF][PDF] Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men.

A Vigelsø, C Prats, T Ploug, F Dela… - Physiological …, 2016 - pdfs.semanticscholar.org
A high VO2max in middle-age is related to high metabolic flexibility and lowered risk of
metabolic diseases. However, the influence of a high VO2max induced by years of regular …

Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men

A Vigelsø, M Gram, C Wiuff, CN Hansen… - European journal of …, 2016 - Springer
Purpose Aging and inactivity lead to skeletal muscle metabolic inflexibility, but the
underlying molecular mechanisms are not entirely elucidated. Therefore, we investigated …