Assessment of GFR is central to clinical practice, research, and public health. Current
Kidney Disease Improving Global Outcomes guidelines recommend measurement of serum …

Rates of many types of severe kidney disease are much higher in Black individuals than
most other ethnic groups. Much of this disparity can now be attributed to genetic variants in …

Background The inclusion of race in equations to estimate the glomerular filtration rate
(GFR) has become controversial. Alternative equations that can be used to achieve similar …

Race and Genetic Ancestry in Medicine US health inequities won't be eliminated by
abandoning the use of race and ethnicity in research and clinical practice, since these …

For almost two decades, equations that use serum creatinine, age, sex, and race to eGFR
have included “race” as Black or non-Black. Given considerable evidence of disparities in …

Background Advancing health equity entails reducing disparities in care. African-American
patients with chronic kidney disease (CKD) have poorer outcomes, including dialysis access …

Populations are often divided categorically into distinct racial/ethnic groups based on social
rather than biological constructs. Genetic ancestry has been suggested as an alternative to …

Racialdiscriminationhasbeenalightningrodf…-atediscourseandsocialactionintheUSfordec…,
ifnot centuries. The recent killings of African Americans by law …

African Americans have a significantly higher risk of developing chronic kidney disease,
especially focal segmental glomerulosclerosis-, than European Americans. Two coding …

Apolipoprotein L1 (APOL1) risk alleles in donor kidneys associate with graft loss, but
whether recipient risk allele expression affects transplant outcomes is unclear. To test …