M Hashimoto, T Nozoe, H Nakaoka… - Proceedings of the …, 2016 - National Acad Sciences
Cellular populations in both nature and the laboratory are composed of phenotypically heterogeneous individuals that compete with each other resulting in complex population …
R Chetrite, H Touchette - Journal of Statistical Mechanics: Theory …, 2015 - iopscience.iop.org
We have shown recently that a Markov process conditioned on rare events involving time- integrated random variables can be described in the long-time limit by an effective Markov …
We derived a new speed limit in population dynamics, which is a fundamental limit on the evolutionary rate. By splitting the contributions of selection and mutation to the evolutionary …
Using a population dynamics inspired by an ensemble of growing cells, a set of fluctuation theorems linking observables measured at the lineage and population levels is derived. One …
P Piho, P Thomas - Science Advances, 2024 - science.org
Phenotypic selection occurs when genetically identical cells are subject to different reproductive abilities due to cellular noise. Such noise arises from fluctuations in reactions …
Phenotype switching with and without sensing environment is a common strategy of organisms to survive in a fluctuating environment. Understanding the evolutionary …
We construct a pathwise formulation of a growing population of cells, based on two different samplings of lineages within the population, namely the forward and backward samplings …
We report that population dynamics in fluctuating environments is characterized by a mathematically equivalent structure to steady-state thermodynamics. By employing the …
Phenotypic variability in a population of cells can work as the bet-hedging of the cells under an unpredictably changing environment, the typical example of which is the bacterial …