A novel effect of Aprepitant: Protection for cisplatin-induced nephrotoxicity and hepatotoxicity
Cisplatin is widely used chemotherapeutic drug and have some serious side effects as
tissue toxicity and nausea and vomiting. Aprepitant is used in clinic as an anti-emetic drug …
tissue toxicity and nausea and vomiting. Aprepitant is used in clinic as an anti-emetic drug …
Urotensin II: an inflammatory cytokine
S Sun, L Liu - Journal of Endocrinology, 2019 - joe.bioscientifica.com
Urotensin II (UII) is a polypeptide molecule with neurohormone-like activity. It has been
confirmed that UII is widely distributed in numerous organs of different animal species from …
confirmed that UII is widely distributed in numerous organs of different animal species from …
Ameliorative effect of gossypin against acute lung injury in experimental sepsis model of rats
Aims Sepsis is a complex pathophysiological event involving systemic inflammatory
response syndrome, multiple organ dysfunction syndrome and tissue damage such as acute …
response syndrome, multiple organ dysfunction syndrome and tissue damage such as acute …
[HTML][HTML] The protective roles of butein on indomethacin induced gastric ulcer in mice
Objective Butein is a potential agent first isolated from Rhus verniciflua that has medicinal
value in East Asia and has been used in the treatment of gastritis, gastric cancer, and …
value in East Asia and has been used in the treatment of gastritis, gastric cancer, and …
In vivo and in vitro cardioprotective effect of gossypin against isoproterenol-induced myocardial infarction injury
The aim of the study was to examine the protective effects and possible mechanism of
gossypin against isoproterenol (ISO)-mediated myocardial damage in vivo and H9c2 cell …
gossypin against isoproterenol (ISO)-mediated myocardial damage in vivo and H9c2 cell …
Does daily fasting shielding kidney on hyperglycemia-related inflammatory cytokine via TNF-α, NLRP3, TGF-β1 and VCAM-1 mRNA expression
This study aimed to investigate the effects of blood glucose control and the kidneys'
functions, depending on fasting, in the streptozotocin-induced diabetes model in rats via …
functions, depending on fasting, in the streptozotocin-induced diabetes model in rats via …
Urotensin receptors as a new target for CLP induced septic lung injury in mice
Sepsis is a life-threatening organ dysfunction condition response resulting in acute lung
injury. Urotensin II (UII), an endogenous vasoactive peptide, is widely distributed in …
injury. Urotensin II (UII), an endogenous vasoactive peptide, is widely distributed in …
Targeting of G-protein coupled receptors in sepsis
Abstract The Third International Consensus Definitions (Sepsis-3) define sepsis as life-
threatening multi-organ dysfunction caused by a dysregulated host response to infection …
threatening multi-organ dysfunction caused by a dysregulated host response to infection …
Potential role of angiotensin converting enzyme/neprilysin pathway and protective effects of omapatrilat for paracetamol‑induced acute liver injury
ZB Aksakalli-Magden, RA Ugan… - Experimental and …, 2022 - spandidos-publications.com
The renin-angiotensin-aldosterone system (RAAS) is an important pathway that contributes
to the pathophysiology of acute liver injury due to paracetamol toxicity. Omapatrilat, a RAAS …
to the pathophysiology of acute liver injury due to paracetamol toxicity. Omapatrilat, a RAAS …
A new approach to sepsis treatment by rasagiline: a molecular, biochemical and histopathological study
Aim We aimed to investigate the effects of rasagiline on acute lung injury that develops in
the sepsis model induced with the cecal ligation and puncture in rats. Main Methods The rats …
the sepsis model induced with the cecal ligation and puncture in rats. Main Methods The rats …