Evaluation of the structural modification of ibuprofen on the penetration release of ibuprofen from a drug-in-adhesive matrix type transdermal patch

P Ossowicz-Rupniewska, P Bednarczyk… - International Journal of …, 2022 - mdpi.com
This study aimed to evaluate the effect of chemical modifications of the structure of active
compounds on the skin permeation and accumulation of ibuprofen [IBU] from the acrylic …

Formulation development and evaluation, in silico PBPK modeling and in vivo pharmacodynamic studies of clozapine matrix type transdermal patches

A Qadir, SU Jan, MH Shoaib, M Sikandar, RI Yousuf… - Scientific Reports, 2025 - nature.com
Clozapine is a potent serotonin receptor antagonist and commonly used for the treatment of
Schizophrenia. The study aimed to develop and optimize the transdermal matrix patch of …

[PDF][PDF] Stability study of super saturable catechin-self nano emulsifying drug delivery system as antidiabetic therapy

S Shiyan, RP Suryani, LN Mulyani… - Biointerface Res Appl …, 2022 - repository.unsri.ac.id
Diabetes mellitus is a metabolic syndrome characterized by hyperglycemic and increased
ROS production, which causes oxidative stress. Catechin isolated from the tea plant has …

Plant leaf mucilage/carrageenan/Eudragit® NE30D blended films: Optimization, characterization, and pharmaceutical application

P Maneewattanapinyo, C Monton… - International Journal of …, 2024 - Elsevier
Mucilage of C. pareira leaves was utilized, being manufactured for use in pharmaceutical
products. Carrageenan and Eudragit® NE30D were used to combined. Glycerin was used …

Improved transdermal delivery of novel cannabinoid-loaded patches using Eudragit matrix

E Wongwad, K Ingkaninan, N Waranuch, C Park… - Journal of Drug Delivery …, 2024 - Elsevier
The main active cannabinoids in extracts of Cannabis sativa L., cannabidiolic acid (CBDA)
and tetrahydrocannabinolic acid (THCA), are known for their pharmacological effects …

[PDF][PDF] Understanding the combination of fractional factorial design and chemometrics analysis for screening super-saturable quercetin-self nano emulsifying …

G Pratiwi, AR Ramadhiani, S Shiyan - Pharmacia, 2022 - pharmacia.pensoft.net
Quercetin is formulated in a super saturable-self-nano emulsifying (SS-SNE) to increase its
stability and bioavailability. This study focuses on the screening design for SS-SNE …

[PDF][PDF] Optimization transdermal patch of polymer combination of chitosan and HPMC-loaded ibuprofen using factorial designs

S Shiyan, MMA Marketama, G Pratiwi - Pharmaciana, 2021 - eprints.uad.ac.id
Ibuprofen is a non-steroidal anti-inflammatory drug that has a disadvantage in its oral use,
such as gastrointestinal disorders, nausea, vomiting and gastric ulcers. Transdermal patch …

Formulation and Characterization of Eplerenone Nanocrystal as Sublingual Fast-dissolving Film

H Kareem, N Rajab - Iraqi Journal of Pharmaceutical …, 2024 - bijps.uobaghdad.edu.iq
Eplerenone, a Class-II according to the biopharmaceutical classification system (BCS), with
poor water solubility, resulting in low bioavailability. To address these limitations, this study …

[PDF][PDF] Skin Penetration of Corn Silk (Zea mays L.) Transdermal Patch on Wistar Mice Skin Using Franz Diffusion Cell.

DF Alzahra, AD Lestari, E Haryadi… - … /Jurnal Farmasi Dan …, 2024 - e-journal.unair.ac.id
Abstract Background: Corn silk (Zea mays L.) contains many active compounds, especially
the flavonoid quercetin which has pharmacological activity as an antihyperlipidemic agent …

[PDF][PDF] FORMULASI DAN OPTIMASI KADAR HYDROXYPROPYL METHYLCELLULOSE K100M DAN POLYVINYL ACETATE DALAM SEDIAAN PATCH …

SA Ilkhawati, ED Ikasari… - Medical Sains: Jurnal …, 2023 - ojs.ummada.ac.id
Propranolol hydrochloride is beta-1 inhibitor prescribed to treat angina, cardiac arrhythmias,
and hypertension. Its oral use has several problems such as first pass effect, a narrow …