Cell survival or death is one critical issue in inflammatory responses. Ferroptosis, which is
characterized by iron-dependent lethal lipid peroxidation, has been found to participate in …

Alzheimer's disease (AD), the most common type of senile dementia, includes the complex
pathogenesis of abnormal deposition of amyloid beta-protein (Aβ), phosphorylated tau (p …

Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic
dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the …

Ischemia–reperfusion (I/R) injury is a disease process that affects several vital organs. There
is widespread agreement that the NLRP3 inflammasome pathway plays a crucial role in the …

Sepsis is a life-threatening condition caused by a dysregulated host-response to
inflammation, although it currently lacks a fully elucidated pathobiology. Iron is a crucial …

Endotoxin-induced acute liver injury (ALI) is a severe disease associated with a poor
prognosis. Therefore, it is urgent to discover new effective therapies to prevent ALI …

Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, is associated with
neuroinflammation. Periodontal disease increases with age; 70.1% of adults 65 years and …

Periodontitis causes inflammatory destructions of tooth-supporting tissue and constitutes a
significant burden on public health. Failing to reserve the tissue damage and bone loss by …

The di-2-pyridylketone thiosemicarbazones demonstrated marked anticancer efficacy,
prompting progression of DpC to clinical trials. However, DpC induced deleterious oxy …

Background The essential oils possess both antimicrobial and anti-inflammatory effects,
therefore they can provide an effective treatment against infections. Essential oils are widely …