Signal transducer and activator of transcription (STAT) 4 and STAT6 play a crucial role in
immune cells by transducing signals from specific cytokine receptors, and inducing …

A hallmark of chronic kidney disease is renal fibrosis, which can result in progressive loss of
kidney function. Currently, there is no effective therapy for renal fibrosis. Therefore, there is …

Billions of cells undergo turnover and die via apoptosis throughout our lifetime. A prompt
clearance of these apoptotic cells and debris by phagocytic cells, a process known as …

The signal transducer and activator of transcription 6 (STAT6) transcription factor promotes
activation of the peroxisome proliferator-activated receptor gamma (PPARγ) pathway in …

Background Epidemiological studies have revealed a link between atopic dermatitis (AD)
and asthma. AS1517499, a selective signal transducer and activation of transcription 6 …

Secreted fungal peptides are known to influence the interactions between the pathogen and
host innate immunity. The aim of this study is to screen and evaluate secreted peptides from …

Signal transducer and activator of transcription 6 (STAT6) promotes an anti-inflammatory
process by inducing the development of M2 macrophages. We investigated whether …

Lung cancer is one of the mortal cancers and the leading cause of cancer-related mortality,
with a cancer survival rate of fewer than 5% in developing nations. This low survival rate can …

Cytokines play a crucial role in the pathophysiology of autoimmune and inflammatory
diseases, with over 50 cytokines undergoing signal transduction through the Signal …

Background and Objectives. Genome‐wide association studies (GWAS) have shown that
cartilage intermediate layer protein 2 (CILP2) is associated with blood lipid levels and …