Inflammation and restenosis in the stent era

FGP Welt, C Rogers - Arteriosclerosis, thrombosis, and vascular …, 2002 - Am Heart Assoc
The pathophysiology of restenosis involves early elements of direct injury to smooth muscle
cells, deendothelialization, and thrombus deposition. Over time, this leads to smooth muscle …

High-sensitivity C-reactive protein: clinical importance

SS Bassuk, N Rifai, PM Ridker - Current problems in cardiology, 2004 - Elsevier
High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation that predicts incident
myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death among …

Molecular basis of restenosis and drug-eluting stents

MA Costa, DI Simon - Circulation, 2005 - Am Heart Assoc
Next is a granulation or cellular proliferation phase. Growth factors are subsequently
released from platelets, leukocytes, and SMCs, which stimulate migration of SMCs from the …

Recognition of the importance of embolization in atherosclerotic vascular disease

EJ Topol, JS Yadav - Circulation, 2000 - Am Heart Assoc
were identified at relatively high frequency (compared with control subjects or patients with
effort angina) in the peripheral blood. 14 Using an experimental canine model, Eguchi et …

Peri-procedural myocardial injury: 2005 update

J Herrmann - European heart journal, 2005 - academic.oup.com
During the past three decades, percutaneous coronary intervention has become one of the
cardinal treatment strategies for stenotic coronary artery disease. Technical advances …

Evaluation of four automated high-sensitivity C-reactive protein methods: implications for clinical and epidemiological applications

WL Roberts, R Sedrick, L Moulton, A Spencer… - Clinical …, 2000 - academic.oup.com
Background: C-reactive protein (CRP) can provide prognostic information about the risk of
developing atherosclerotic complications in apparently healthy patients. This new clinical …

Preprocedural serum levels of C-reactive protein predict early complications and late restenosis after coronary angioplasty

A Buffon, G Liuzzo, LM Biasucci, P Pasqualetti… - Journal of the American …, 1999 - jacc.org
OBJECTIVES We sought to investigate whether early and late outcome after percutaneous
transluminal coronary angioplasty (PTCA) could be predicted by baseline levels of acute …

The novel role of C-reactive protein in cardiovascular disease: risk marker or pathogen

AM Wilson, MC Ryan, AJ Boyle - International journal of cardiology, 2006 - Elsevier
C-reactive protein (CRP) is a non-specific biomarker of inflammation. Recent research has
shown that inflammation is an important step in the genesis of atherosclerosis, and is …

Incremental prognostic value of elevated baseline C-reactive protein among established markers of risk in percutaneous coronary intervention

DP Chew, DL Bhatt, MA Robbins, MS Penn… - Circulation, 2001 - Am Heart Assoc
Background Established methods of risk assessment in percutaneous coronary intervention
have focused on clinical and anatomical lesion characteristics. Emerging evidence indicates …

Inflammation and restenosis after percutaneous coronary interventions

K Toutouzas, A Colombo, C Stefanadis - European heart journal, 2004 - academic.oup.com
The role of inflammation in the development of restenosis after percutaneous coronary
interventions has been investigated in several studies. There is an interaction of …