Pharmacology of cardiac potassium channels
Cardiac K+ channels are membrane-spanning proteins that allow the passive movement of
K+ ions across the cell membrane along its electrochemical gradient. They regulate the …
K+ ions across the cell membrane along its electrochemical gradient. They regulate the …
The KCNQ1 potassium channel: from gene to physiological function
T Jespersen, M Grunnet, SP Olesen - Physiology, 2005 - journals.physiology.org
The voltage-gated KCNQ1 (KvLQT1, Kv7. 1) potassium channel plays a crucial role in
shaping the cardiac action potential as well as in controlling the water and salt homeostasis …
shaping the cardiac action potential as well as in controlling the water and salt homeostasis …
[HTML][HTML] Structural basis of human KCNQ1 modulation and gating
J Sun, R MacKinnon - Cell, 2020 - cell.com
KCNQ1, also known as Kv7. 1, is a voltage-dependent K+ channel that regulates gastric
acid secretion, salt and glucose homeostasis, and heart rhythm. Its functional properties are …
acid secretion, salt and glucose homeostasis, and heart rhythm. Its functional properties are …
Food security in Australia in an era of neoliberalism, productivism and climate change
For over 150 years Australia has exported bulk, undifferentiated, commodities such as wool,
wheat, meat and sugar to the UK and more recently to Japan, Korea, and the Middle East. It …
wheat, meat and sugar to the UK and more recently to Japan, Korea, and the Middle East. It …
[HTML][HTML] The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods
Representing a basal branch of arachnids, scorpions are known as 'living fossils' that
maintain an ancient anatomy and are adapted to have survived extreme climate changes …
maintain an ancient anatomy and are adapted to have survived extreme climate changes …
Computational biology in the study of cardiac ion channels and cell electrophysiology
Y Rudy, JR Silva - Quarterly reviews of biophysics, 2006 - cambridge.org
1. Prologue 582. The Hodgkin–Huxley formalism for computing the action potential 592.1
The axon action potential model 592.2 Cardiac action potential models 623. Ion-channel …
The axon action potential model 592.2 Cardiac action potential models 623. Ion-channel …
Orai proteins interact with TRPC channels and confer responsiveness to store depletion
Y Liao, C Erxleben, E Yildirim… - Proceedings of the …, 2007 - National Acad Sciences
The TRPC (C-type transient receptor potential) class of ion channels has been hypothesized
to participate in store-operated Ca2+ entry (SOCE). Recently, however, STIM1 and Orai1 …
to participate in store-operated Ca2+ entry (SOCE). Recently, however, STIM1 and Orai1 …
Stoichiometry of the KCNQ1-KCNE1 ion channel complex
K Nakajo, MH Ulbrich, Y Kubo… - Proceedings of the …, 2010 - National Acad Sciences
The KCNQ1 voltage-gated potassium channel and its auxiliary subunit KCNE1 play a crucial
role in the regulation of the heartbeat. The stoichiometry of KCNQ1 and KCNE1 complex has …
role in the regulation of the heartbeat. The stoichiometry of KCNQ1 and KCNE1 complex has …
The MinK-related peptides
ZA McCrossan, GW Abbott - Neuropharmacology, 2004 - Elsevier
Voltage-gated potassium (Kv) channels mediate rapid, selective diffusion of K+ ions through
the plasma membrane, controlling cell excitability, secretion and signal transduction. KCNE …
the plasma membrane, controlling cell excitability, secretion and signal transduction. KCNE …
Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel
C Kang, C Tian, FD Sönnichsen, JA Smith… - Biochemistry, 2008 - ACS Publications
KCNE1 is a single-span membrane protein that modulates the voltage-gated potassium
channel KCNQ1 (KV7. 1) by slowing activation and enhancing channel conductance to …
channel KCNQ1 (KV7. 1) by slowing activation and enhancing channel conductance to …