Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Colistin resistance is a globalized sensible issue because it has been considered a drug of
the last‐line resort to treat drug‐resistant bacterial infections. The product of the mobilized …

Until recently, the polymyxin antibiotics were used sparingly due to dose limiting toxicities.
However, the lack of therapeutic alternatives for infections caused by highly resistant Gram …

Resistance to last resort drugs such as carbapenem and colistin is a serious global health
threat. This study investigated carbapenem and colistin resistance in 583 non-duplicate …

Purpose Carbapenemases-producing Klebsiella pneumoniae are challenging antimicrobial
therapy of hospitalised patients, which is further complicated by colistin resistance. This …

Background: The resistance to colistin and carbapenems in Klebsiella pneumoniae
infections have been associated with increased morbidity and mortality worldwide. A …

The emergence of genetic mutations in chromosomal genes and the transmissible plasmid-
mediated colistin resistance gene may have helped in the spread of colistin resistance …

Background The emergence of carbapenem-resistant and hypervirulent hypermucoviscous
Klebsiella pneumoniae strains poses a significant public health challenge. We determined …

Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CR-KP) is an urgent
public health issue in Italy. This pattern of resistance is due mainly to dissemination of …

Klebsiella pneumoniae is one of the most important pathogens concerned with multidrug
resistance in healthcare-associated infections. The treating of infections caused by this …