Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Brain metastasis (BM) predominantly occurs in triple-negative (TN) and epidermal growth
factor 2 (HER2)-positive breast cancer (BC) patients, and currently, there is an unmet need …

Liver metastasis (LM) severely affects gastric cancer (GC) patients' prognosis. Small
extracellular vesicles (sEVs) play key roles in intercellular communication. Specific sEV …

There is a strong body of evidence by several translational studies which demonstrate the
potential of circulating miRNAs as a potential biomarker in oncology. However, recent …

An increasing number of studies have demonstrated that circular RNAs (circRNAs), as
promising therapeutic targets, are essential for diverse human diseases, especially cancer …

Cervical cancer is one of the most common gynecological malignant tumors worldwide, for
which chemotherapeutic strategies are limited due to their non-specific cytotoxicity and drug …

The concept of epithelial–mesenchymal plasticity (EMP), which describes the dynamic flux
within the spectrum of phenotypic states that invasive carcinoma cells may reside, is being …

Postmenopausal osteoporosis, the most common type of primary osteoporosis, poses a
significant threat to women's health worldwide. However, detailed molecular mechanism …

Background Skeletal muscle regeneration is a complex process regulated by many
cytokines and growth factors. Among the important signaling pathways regulating the …

The critical importance of circular RNAs (circRNAs) in human cancers, including ovarian
cancer, has been discovered in the recent years. However, the roles of circ_0007841 in …