Macrophages play a central role in tuberculosis, as the site of primary infection, inducers
and effectors of inflammation, innate and adaptive immunity, as well as mediators of tissue …

Bacterial persisters are a subpopulation of cells that exhibit phenotypic resistance during
exposure to a lethal dose of antibiotics. They are difficult to target and thought to contribute …

Background Antiretroviral therapy (ART) is known to reduce tuberculosis (TB) incidence
among people living with HIV (PLWH). However, studies describing the impact of long-term …

Tuberculosis (TB), caused by Mycobacterium tuberculosis infection, remains a major cause
of mortality and morbidity worldwide. One-third of the world population is infected with M …

Background Mycobacterium tuberculosis has co-evolved with the human host, adapting to
exploit the immune system for persistence and transmission. While immunity to tuberculosis …

Tuberculosis (TB) remains as a major threat to human health worldwide despite of the
availability of standardized antibiotic therapy. One of the characteristic of pathogenic …

Mycobacterium tuberculosis is a chronic infectious disease pathogen. To date, tuberculosis
is a major infectious disease that endangers human health. To better prevent and treat …

Abstract Persistence of Mycobacterium tuberculosis (Mtb) is one of the challenges to
successful treatment of tuberculosis (TB). In vitro models of non-replicating Mtb are used to …

Adipose tissues were shown to host Mycobacterium tuberculosis which is persisting inside
mature adipocytes. It remains unknown whether this holds true for Mycobacterium canettii, a …

Adipose tissue is best understood from the body composition perspective, where body
weight is divided into two functional component parts referred to as fat mass (mainly …