The existence of disintegrins, non-enzymatic, small molecular weight proteins from viper
venom, has been known for 2 decades, and their impact on cellular research has been …

To date, there have been few systematic studies of the antiplatelet and/or anticoagulant
effects of natural products. According to the Natural Medicines Comprehensive Database …

Snake venom proteins are broadly investigated in the different areas of life science. Direct
interaction of these compounds with cells may involve a variety of mechanisms that result in …

Alternagin-C (ALT-C), a disintegrin-like protein purified from the venom of the Brazilian
snake Bothrops alternatus, interacts with the major collagen I receptor, the α 2 β 1 integrin …

The α5β1 integrin is one of the major fibronectin receptors which plays an essential role in
the adhesion of normal and tumor cells to extracellular matrix. Here, we describe the …

Two new furostanol saponins,(25 R)-26-O-β-d-glucopyranosyl-5α-furostan-2α, 3β, 22α, 26-
tetraol 3-O-{β-d-galactopyranosyl-(1→ 2)-O-[β-d-xylopyranosyl-(1→ 3)]-O-β-d …

1. ABSTRACT A monomeric RGD-disintegrin was recently identified from a cDNA library
from the venom gland of Bothrops alternatus. The corresponding 12 kDarecombinant …

Extracellular matrix proteins and cell adhesion receptors (integrins) play essential roles in
the regulation of cell adhesion and migration. Interactions of integrins with the extracellular …

We previously demonstrated that jarastatin (JT), a new disintegrin from Bothrops jararaca
venom, altered actin dynamics in human polymorphonuclear neutrophils (PMNs) and …

Gloriosaols A–C, isolated from Yucca gloriosa (Agavaceae), are novel phenolic compounds
structurally related to resveratrol. In the present study, we show that gloriosaols possess …