The molecular mechanisms and rational design of anti-diabetic vanadium compounds
X Niu, R Xiao, N Wang, Z Wang… - Current topics in …, 2016 - ingentaconnect.com
Vanadium compounds are promising anti-diabetic agents. Although BEOV was not able to
succeed in phase II clinical trial, great progresses have been made in the past three …
succeed in phase II clinical trial, great progresses have been made in the past three …
钒化合物通过不同方式刺激线粒体活性氧生成
施喆， 刘会雪， 杨晓达 - 中国药学(英文版), 2011 - jcps.bjmu.edu.cn
钒化合物在癌症及糖尿病治疗中显示出其潜在的可能而受到人们的关注, 但是其毒性限制了其
作为药物的进一步发展. 已有研究表明钒通过影响线粒体功能诱导的氧化应激是钒化合物毒性的 …
作为药物的进一步发展. 已有研究表明钒通过影响线粒体功能诱导的氧化应激是钒化合物毒性的 …
钒化合物调节RAW264. 7 细胞中热休克蛋白60 诱导的IL-6 释放
郭巍， 杨晓达 - 中国药学(英文版), 2015 - jcps.bjmu.edu.cn
钒化合物是具有前景的抗糖尿病候选药物, 但其药理作用机制尚未完全阐明. 在I 型和II
型糖尿病发病过程中, 炎症和自免疫紊乱可能发挥了重要作用; 其中热休克蛋白60 (HSP60) …
型糖尿病发病过程中, 炎症和自免疫紊乱可能发挥了重要作用; 其中热休克蛋白60 (HSP60) …
The long-term toxicity and hypoglycemic effect of vanadyl complexes on non-diabetic and type II diabetic mice
Z Wang, N Wang, M Huang, X Yang - Journal of Chinese …, 2015 - jcps.bjmu.edu.cn
Vanadium compounds are promising anti-diabetic agents. However, the concern in the
toxicity, especially the long-term renal side effect along with diabetic status, is restricting the …
toxicity, especially the long-term renal side effect along with diabetic status, is restricting the …
Vanadium regulates HSP60-induced IL-6 release from RAW264. 7 cells in a dose-dependent manner
W Guo, X Yang - Journal of Chinese Pharmaceutical Sciences, 2015 - jcps.bjmu.edu.cn
Vanadium compounds are promising anti-diabetic agents. However, the underlying
mechanisms have not been fully elucidated. Inflammation and auto-immune disorders play …
mechanisms have not been fully elucidated. Inflammation and auto-immune disorders play …