Histone variants and modifications during abiotic stress response
R Nunez-Vazquez, B Desvoyes… - Frontiers in Plant …, 2022 - frontiersin.org
Plants have developed multiple mechanisms as an adaptive response to abiotic stresses,
such as salinity, drought, heat, cold, and oxidative stress. Understanding these regulatory …
such as salinity, drought, heat, cold, and oxidative stress. Understanding these regulatory …
Epigenetic regulation and therapeutic targets in the tumor microenvironment
Z Xie, Z Zhou, S Yang, S Zhang, B Shao - Molecular Biomedicine, 2023 - Springer
The tumor microenvironment (TME) is crucial to neoplastic processes, fostering proliferation,
angiogenesis and metastasis. Epigenetic regulations, primarily including DNA and RNA …
angiogenesis and metastasis. Epigenetic regulations, primarily including DNA and RNA …
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
G Cao, L Ma, Z Zhang, X Wang, J Hua… - Acta Pharmacologica …, 2023 - nature.com
Small-cell lung cancer (SCLC) is an aggressive high-grade neuroendocrine carcinoma of
the lung associated with early metastasis and an exceptionally poor prognosis. Little …
the lung associated with early metastasis and an exceptionally poor prognosis. Little …
[HTML][HTML] Roles of Histone H2B, H3 and H4 Variants in Cancer Development and Prognosis
PM Lai, X Gong, KM Chan - International Journal of Molecular Sciences, 2024 - mdpi.com
Histone variants are the paralogs of core histones (H2A, H2B, H3 and H4). They are stably
expressed throughout the cell cycle in a replication-independent fashion and are capable of …
expressed throughout the cell cycle in a replication-independent fashion and are capable of …
Histone Chaperones in Cancer
MB Shirude, D Dutta - Handbook of Oncobiology: From Basic to Clinical …, 2023 - Springer
Histone epigenetics has three layers including histone modifications, histone variants, and
histone chaperones. Unlike the first two components, limited information on histone …
histone chaperones. Unlike the first two components, limited information on histone …
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3′-UTR in de-differentiated and undifferentiated hepatocyte
Replication-dependent histones have a stem-loop structure at the 3′ end of messenger
RNA (mRNA) and are stabilized by stem-loop binding protein (SLBP). Moreover, loss of …
RNA (mRNA) and are stabilized by stem-loop binding protein (SLBP). Moreover, loss of …