The 97-megabase genomic sequence of the nematode Caenorhabditis elegans reveals
over 19,000 genes. More than 40 percent of the predicted protein products find significant …

Developmental stages in multicellular organisms proceed according to a temporally and
spatially precise pattern of gene expression. It has become evident that changes within the …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

An understanding of the basic defect in the inherited disorder cystic fibrosis requires cloning
of the cystic fibrosis gene and definition of its protein product. In the absence of direct …

A highly conserved repetitive DNA sequence,(TTAGGG) n, has been isolated from a human
recombinant repetitive DNA library. Quantitative hybridization to chromosomes sorted by …

An improved lithium acetate (LiAc)/single‐stranded DNA (SS‐DNA)/polyethylene glycol
(PEG) protocol which yields> 1× 106 transformants/μg plasmid DNA and the original …

X-linked agammaglobulinaemia (XLA) is a human immunodeficiency caused by failure of
pre-B cells in the bone marrow to develop into circulating mature B cells. A novel gene has …

A method, using LiAc to yield competent cells, is described that increased the efficiency of
genetic transformation of intact cells of Saccharomyces cerevisiae to more than 1× 10 5 …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in
Medicine returns as one of the most favored texts in this fascinating and rapidly evolving …