[HTML][HTML] Trustworthy AI: closing the gap between development and integration of AI systems in ophthalmic practice

C González-Gonzalo, EF Thee, CCW Klaver… - Progress in retinal and …, 2022 - Elsevier
An increasing number of artificial intelligence (AI) systems are being proposed in
ophthalmology, motivated by the variety and amount of clinical and imaging data, as well as …

Solar radiation exposure and outdoor work: an underestimated occupational risk

A Modenese, L Korpinen, F Gobba - International journal of …, 2018 - mdpi.com
A considerably high number of outdoor workers worldwide are constantly exposed for the
majority of their working life to solar radiation (SR); this exposure is known to induce various …

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

M Hata, EMMA Andriessen, M Hata, R Diaz-Marin… - Science, 2023 - science.org
Age-related macular degeneration is a prevalent neuroinflammatory condition and a major
cause of blindness driven by genetic and environmental factors such as obesity. In diseases …

Pachychoroid neovasculopathy

CE Pang, KB Freund - Retina, 2015 - journals.lww.com
Purpose: To report 3 cases of pachychoroid neovasculopathy, a form of Type 1 (sub-retinal
pigment epithelium) neovascularization, occurring over areas of increased choroidal …

The retinal pigment epithelium in visual function

O Strauss - Physiological reviews, 2005 - journals.physiology.org
Located between vessels of the choriocapillaris and light-sensitive outer segments of the
photoreceptors, the retinal pigment epithelium (RPE) closely interacts with photoreceptors in …

Quantitative assessment of the retinal microvasculature using optical coherence tomography angiography

Z Chu, J Lin, C Gao, C Xin, Q Zhang… - … of biomedical optics, 2016 - spiedigitallibrary.org
Optical coherence tomography angiography (OCTA) is clinically useful for the qualitative
assessment of the macular microvasculature. However, there is a need for comprehensive …

Age-related macular degeneration

RD Jager, WF Mieler, JW Miller - New England Journal of …, 2008 - Mass Medical Soc
Age-related macular degeneration is the leading cause of irreversible blindness in people
50 years of age or older in the developed world. This article reviews the clinical and …

Complement factor H polymorphism and age-related macular degeneration

AO Edwards, R Ritter III, KJ Abel, A Manning… - Science, 2005 - science.org
Age-related macular degeneration (AMD) is a common, late-onset, and complex trait with
multiple risk factors. Concentrating on a region harboring a locus for AMD on 1q25-31, the …

[HTML][HTML] VEGFR1 signaling in retinal angiogenesis and microinflammation

A Uemura, M Fruttiger, PA d'Amore, S De Falco… - Progress in retinal and …, 2021 - Elsevier
Five vascular endothelial growth factor receptor (VEGFR) ligands (VEGF-A,-B,–C,-D, and
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

GS Hageman, DH Anderson… - Proceedings of the …, 2005 - National Acad Sciences
Age-related macular degeneration (AMD) is the most frequent cause of irreversible
blindness in the elderly in developed countries. Our previous studies implicated activation of …