N Singh, G Cheve, MA Avery… - Current pharmaceutical …, 2007 - ingentaconnect.com
The 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway for isoprenoid biosynthesis has come under increased scrutiny as a target for novel antimalarial, antibacterial and herbicidal …
The methylerythritol phosphate pathway to isoprenoids, an alternate biosynthetic route present in many bacteria, algae, plants, and the malarial parasite Plasmodium falciparum …
J Wiesner, H Jomaa - Current drug targets, 2007 - ingentaconnect.com
In Plasmodium falciparum the biosynthesis of isoprenoids is achieved by the mevalonate- independent 1-deoxy-D-xylulose 5-phosphate (DOXP) pathway. The enzymes of the DOXP …
P Heidler, A Link - Bioorganic & medicinal chemistry, 2005 - Elsevier
In 1971 Kenner et al. introduced the safety-catch principle into solid phase peptide synthesis. Thus two contradicting needs were addressed. On the one hand, sufficient …
BC Bookser, NB Raffaele - The Journal of Organic Chemistry, 2007 - ACS Publications
The Vorbrüggen glycosylation reaction was adapted into a one-step 5 min/130° C microwave assisted reaction. Triethanolamine in acetontrile containing 2% water was …
VI Tararov, A Tijsma, SV Kolyachkina… - European Journal of …, 2015 - Elsevier
In this study, we demonstrate that N 6-isopentenyladenosine, which essentially is a plant cytokinin-like compound, exerts a potent and selective antiviral effect on the replication of …
D Gießmann, P Heidler, T Haemers… - Chemistry & …, 2008 - Wiley Online Library
The conversion of 1‐deoxy‐d‐xylulose‐5‐phosphate (DOXP) to 2‐C‐methyl‐d‐erythritol‐4‐ phosphate (MEP) is effectively blocked by 1‐deoxy‐d‐xylulose‐5‐phosphate …