Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …

Amyloid plaques, mainly composed of abnormally aggregated amyloid β-protein (Aβ) in the
brain parenchyma, and neurofibrillary tangles (NFTs), consisting of hyperphosphorylated tau …

The NLRP3 inflammasome plays a central role in antimicrobial defense as well as in the
context of sterile inflammatory conditions. NLRP3 activity is governed by two independent …

Inflammation is involved in tumor development and progression as well as antitumor
response to therapy. In the past decade, the crosstalk between inflammation, immunity, and …

Inflammatory pathways drive atherogenesis and link conventional risk factors to
atherosclerosis and its complications. One inflammatory mediator has come to the fore as a …

Aging-related, nonresolving inflammation in both the central nervous system (CNS) and
periphery predisposes individuals to the development of neurodegenerative disorders …

Abstract The NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome is
an immunological sensor that detects a wide range of microbial-and host-derived signals …

Over the recent years, much has been unraveled about the pro-inflammatory properties of
various mitochondrial molecules once they are leaving the mitochondrial compartment. On …

There is a great clinical need to identify the underlying mechanisms, as well as related
biomarkers, and treatment targets, for traumatic brain injury (TBI). Neuroinflammation is a …

Atherosclerosis (AS) is an inflammatory disease linked to endothelial dysfunction. Melatonin
is reported to possess substantial anti‐inflammatory properties, which has proven to be …