Amphiphilic copolymers consisting of alternating hydrophilic and hydrophobic units account
for a major recent methodical breakthrough in the investigations of membrane proteins …

Nucleosides play central roles in all facets of life, from metabolism to cellular signaling.
Because of their physiochemical properties, nucleosides are lipid bilayer impermeable and …

The use of styrene maleic acid co-polymer (SMA) for membrane protein extraction and
purification has grown in recent years. SMA inserts in the membrane and assembles into …

Rapamycin and FK506 are macrocyclic natural products with an extraordinary mode of
action, in which they form binary complexes with FK506-binding protein (FKBP) through a …

The Augustine antigen (referred to as AUG) is a newly recognized" system" antigen for ISBT
in 2016, and the system has 2 antigens, in which AUG2 is the high frequency antigen Ata in …

Styrene maleic acid (SMA) polymers have proven to be very successful for the extraction of
membrane proteins, forming SMA lipid particles (SMALPs), which maintain a lipid bilayer …

Membrane proteins account for a third of the eukaryotic proteome, but are greatly under-
represented in the Protein Data Bank. Unfortunately, recent technological advances in X-ray …

Applications of nanomaterials to biological systems have received increased interest in the
past decades. In particular, bacterial cellulose nanofibers can be utilized in a broad range of …

In the twelve years since styrene maleic acid (SMA) was first used to extract and purify a
membrane protein within a native lipid bilayer, this technological breakthrough has provided …

The human equilibrative nucleoside transporter-1 (hENT1) is important for the entry of anti-
cancer and anti-viral nucleoside analog therapeutics into the cell, and thus for their efficacy …