Epithelial tissue homeostasis is closely associated with the self-renewal and differentiation
behaviors of epithelial stem cells (ESCs). p63, a well-known marker of ESCs, is an …

Pulmonary fibrosis (PF) is a chronic and relentlessly progressive interstitial lung disease in
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …

Adult lung resident stem/progenitor cells, including P63+ progenitor cells, have
demonstrated the capacity for regeneration of lung epithelium in preclinical models. Here …

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with limited therapeutic
options. Current evidence suggests that IPF may be initiated by repeated epithelial injuries …

Pulmonary fibrosis (PF) is a chronic, progressive, fibrotic interstitial disease of the lung with
poor prognosis and without effective treatment currently. Data from previous coronavirus …

Silica-induced lung epithelial injury and fibrosis are vital pathogeneses of silicosis. Although
the NOD-like receptor protein 3 (NLRP3) inflammasome contributes to silica-induced …

Pulmonary fibrosis (PF) is a chronic and progressive lung disease characterized by
extensive alterations of cellular fate and function and excessive accumulation of …

Fibrosis is a pathological process that affects multiple organs and is considered one of the
major causes of morbidity and mortality in multiple diseases, resulting in an enormous …

Idiopathic pulmonary fibrosis is an aging-related, chronic lung disease, with unclear
pathogenesis and no effective treatment. One of the triggering factors in cell aging is …

Acute respiratory distress syndrome (ARDS) is characterized by an exacerbated
inflammatory response, severe damage to the alveolar-capillary barrier and a secondary …