Applications of focused ultrasound in the brain: from thermoablation to drug delivery

Y Meng, K Hynynen, N Lipsman - Nature Reviews Neurology, 2021 - nature.com
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …

Obsessive-compulsive disorder: puzzles and prospects

TW Robbins, MM Vaghi, P Banca - Neuron, 2019 - cell.com
Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

[HTML][HTML] The mouse cortico–basal ganglia–thalamic network

NN Foster, J Barry, L Korobkova, L Garcia, L Gao… - Nature, 2021 - nature.com
The cortico–basal ganglia–thalamo–cortical loop is one of the fundamental network motifs in
the brain. Revealing its structural and functional organization is critical to understanding …

Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective

DL Pauls, A Abramovitch, SL Rauch… - Nature Reviews …, 2014 - nature.com
Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …

Brain circuitry of compulsivity

OA Van den Heuvel, G van Wingen… - European …, 2016 - Elsevier
Compulsivity is associated with alterations in the structure and the function of parallel and
interacting brain circuits involved in emotional processing (involving both the reward and the …

Goal-directed learning and obsessive–compulsive disorder

CM Gillan, TW Robbins - Philosophical Transactions of …, 2014 - royalsocietypublishing.org
Obsessive–compulsive disorder (OCD) has become a paradigmatic case of goal-directed
dysfunction in psychiatry. In this article, we review the neurobiological evidence, historical …

Neuroanatomy of autism

DG Amaral, CM Schumann, CW Nordahl - Trends in neurosciences, 2008 - cell.com
Autism spectrum disorder is a heterogeneous, behaviorally defined, neurodevelopmental
disorder that occurs in 1 in 150 children. Individuals with autism have deficits in social …

Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited

L Menzies, SR Chamberlain, AR Laird… - Neuroscience & …, 2008 - Elsevier
Obsessive-compulsive disorder (OCD) is a common, heritable and disabling
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …

Epidemiology of anxiety disorders

RC Kessler, AM Ruscio, K Shear… - Behavioral neurobiology of …, 2010 - Springer
This chapter presents an overview of the descriptive epidemiology of anxiety disorders
based on recently completed surveys of the general population. The overall prevalence of …

Obsessive-compulsive disorder

JS Abramowitz, S Taylor, D McKay - The Lancet, 2009 - thelancet.com
Obsessive-compulsive disorder is a severe and disabling clinical condition that usually
arises in late adolescence or early adulthood and, if left untreated, has a chronic course …