European Society for Sexual Medicine consensus statement on the use of the cavernous nerve injury rodent model to study postradical prostatectomy erectile …
Introduction Rodent animal models are currently the most used in vivo model in translational
studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical …
studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical …
The Cavernous Nerve Injury Rat Model: A Pictorial Essay on Post-Radical Prostatectomy Erectile Dysfunction Research
Understanding and addressing post-radical prostatectomy (RP) erectile dysfunction (ED) is
of paramount importance for clinicians. Cavernous nerve (CN) injury rat model studies have …
of paramount importance for clinicians. Cavernous nerve (CN) injury rat model studies have …
[HTML][HTML] Efficacy of a red-light controllable nitric oxide releaser for neurogenic erectile dysfunction: a study using a rat model of cavernous nerve Injury
Purpose Neurogenic erectile dysfunction (ED) is a common side effect of radical
prostatectomy (RP) because of cavernous nerve damage. In these patients, the production …
prostatectomy (RP) because of cavernous nerve damage. In these patients, the production …
Inhibition of multidrug resistance proteins by MK571 restored the erectile function in obese mice through cGMP accumulation
MG de Oliveira, GR Passos, ET de Gomes… - …, 2023 - Wiley Online Library
Background Intracellular levels of cyclic nucleotides can also be controlled by the action of
multidrug resistance protein types 4 (MRP4) and 5 (MRP5). To date, no studies evaluated …
multidrug resistance protein types 4 (MRP4) and 5 (MRP5). To date, no studies evaluated …
An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats
Y Ge, D Hu, Y Xi, H Wang, T Xia, J Chen, X Pu, H Xiao - Life Sciences, 2023 - Elsevier
Aim Over the years, the cavernous nerve (CN) crushing injury rat model has been frequently
used for studying post-radical prostatectomy erectile dysfunction (pRP-ED). However …
used for studying post-radical prostatectomy erectile dysfunction (pRP-ED). However …
Research advances in Peyronie's disease: a comprehensive review on genomics, pathways, phenotypic manifestation, and therapeutic targets
J Chi, W Bi, K Lou, J Ma, J Wu… - Sexual Medicine Reviews, 2024 - academic.oup.com
Introduction Penile induration disease, commonly known as Peyronie's disease (PD), is a
connective tissue disorder that affects the penis, leading to the development of fibrous …
connective tissue disorder that affects the penis, leading to the development of fibrous …
Caveolin-1 scaffolding domain-derived peptide enhances erectile function by regulating oxidative stress, mitochondrial dysfunction, and apoptosis of corpus …
Y Xi, Z Feng, T Xia, Y Hong, J Wu, J Chen, Y Ge… - Life Sciences, 2024 - Elsevier
Aim Increased corpus cavernosum smooth muscle cells (CCSMCs) apoptosis in the penis
due to cavernous nerve injury (CNI) is a crucial contributor to erectile dysfunction (ED) …
due to cavernous nerve injury (CNI) is a crucial contributor to erectile dysfunction (ED) …
A systematic review on rho-kinase as a potential therapeutic target for the treatment of erectile dysfunction
KA Zewdie, MA Ayza, BA Tesfaye… - … and Reports in …, 2020 - Taylor & Francis
Background Erectile dysfunction (ED) is a common clinical condition with limited treatment
options. The main aim of the present systematic review was to synthesize information on …
options. The main aim of the present systematic review was to synthesize information on …
Combination of LIM-kinase 2 and Jun amino-terminal kinase inhibitors improves erectile function in a rat model of cavernous nerve injury
SW Kim, J Lee, J Park, JS Chai, S Oh, JS Paick… - Urology, 2019 - Elsevier
Objective To determine if combined administration of LIMK2 and JNK inhibitors in a rat
model of erectile dysfunction induced by cavernosal nerve (CN) injury could restore erectile …
model of erectile dysfunction induced by cavernosal nerve (CN) injury could restore erectile …
Restoration of erectile function by a combination of antiapoptosis by JNK inhibitor and preservation of smooth muscle or endothelium by hepatocyte growth factor in a …
SW Kim, J Lee, S Oh, H Son, MC Cho - The Prostate, 2022 - Wiley Online Library
Background Because of structural alterations in the corpus cavernosum after radical
prostatectomy (RP), post‐RP erectile dysfunction remains a very difficult condition to treat …
prostatectomy (RP), post‐RP erectile dysfunction remains a very difficult condition to treat …