Depression in neurodegenerative diseases: Common mechanisms and current treatment options

CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Amphetamine toxicities: classical and emerging mechanisms

BK Yamamoto, A Moszczynska… - Annals of the New York …, 2010 - Wiley Online Library
The drugs of abuse, methamphetamine and MDMA, produce long‐term decreases in
markers of biogenic amine neurotransmission. These decreases have been traditionally …

Stress, depression and Parkinson's disease

AM Hemmerle, JP Herman, KB Seroogy - Experimental neurology, 2012 - Elsevier
In this review, we focus on the relationship among Parkinson's disease (PD), stress and
depression. Parkinson's disease patients have a high risk of developing depression, and it is …

LC–MS-based urinary metabolite signatures in idiopathic Parkinson's disease

H Luan, LF Liu, N Meng, Z Tang, KK Chua… - Journal of proteome …, 2015 - ACS Publications
Increasing evidence has shown that abnormal metabolic phenotypes in body fluids reflect
the pathogenesis and pathophysiology of Parkinson's disease (PD). These body fluids …

Environmental factors as modulators of neurodegeneration: Insights from gene–environment interactions in Huntington's disease

C Mo, AJ Hannan, T Renoir - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Unlike many other neurodegenerative diseases with established gene–environment
interactions, Huntington's disease (HD) is viewed as a disorder governed by genetics. The …

Cortisol levels, motor, cognitive and behavioral symptoms in Parkinson's disease: a systematic review

NM Soares, GM Pereira, V Altmann… - Journal of Neural …, 2019 - Springer
Parkinson's disease (PD) is a progressive and multifactorial neurodegenerative disease. It
has been suggested that a dysregulation of the hypothalamic–pituitary–adrenal axis (HPA) …

Targeting psychologic stress signaling pathways in Alzheimer's disease

HS Futch, CL Croft, VQ Truong, EG Krause… - Molecular …, 2017 - Springer
Alzheimer's Disease (AD) is the most prevalent progressive neurodegenerative disease; to
date, no AD therapy has proven effective in delaying or preventing the disease course. In the …

[HTML][HTML] Association between depression and risk of Parkinson's disease in South Korean adults

W Jeong, H Kim, JH Joo, SI Jang, EC Park - Journal of affective disorders, 2021 - Elsevier
Background Depression is considered a predictive factor for cognitive impairments. At the
same time, Parkinson's disease (PD) is a growing public health problem. The aim of this …

Gestational restraint stress and the developing dopaminergic system: an overview

CJ Baier, MR Katunar, E Adrover, ME Pallarés… - Neurotoxicity …, 2012 - Springer
Prenatal stress exerts a strong impact on fetal brain development in rats impairing
adaptation to stressful conditions, subsequent vulnerability to anxiety, altered sexual …

Glucocorticoid receptor antagonist CORT113176 attenuates motor and neuropathological symptoms of Huntington's disease in R6/2 mice

M Gentenaar, FL Meulmeester, XR van der Burg… - Experimental …, 2024 - Elsevier
Huntington's Disease (HD) is a progressive neurodegenerative disease caused by a
mutation in the huntingtin gene. The mutation leads to a toxic gain of function of the mutant …