Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …

DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

The epidemiology of hepatitis C virus in Iran: systematic review and meta-analyses

S Mahmud, V Akbarzadeh, LJ Abu-Raddad - Scientific reports, 2018 - nature.com
The aim of this study was to characterize hepatitis C virus (HCV) epidemiology in Iran and
estimate the pooled mean HCV antibody prevalence in different risk populations. We …

[HTML][HTML] Evaluation of iron overload by cardiac and liver T2* in β-thalassemia: Correlation with serum ferritin, heart function and liver enzymes

HK Heris, B Nejati, K Rezazadeh, H Sate… - … of cardiovascular and …, 2021 - ncbi.nlm.nih.gov
Introduction: In this study, we aimed to assess the relationship of cardiac and hepatic T2*
magnetic resonance imaging (MRI) values as a gold standard for detecting iron overload …

[HTML][HTML] Prevalence of anti HCV infection in patients with Beta-thalassemia in isfahan-iran

B Ataei, M Hashemipour, N Kassaian… - … journal of preventive …, 2012 - ncbi.nlm.nih.gov
Objectives: Hepatitis C virus (HCV) is the major cause of post-transfusion hepatitis infection
(PTH). Patients with thalassemia major are at high risk of hepatitis C due to the blood …

[HTML][HTML] Clinical and biochemical assessment of liver function test and its correlation with serum ferritin levels in transfusion-dependent thalassemia patients

M Al-Moshary, N Imtiaz, E Al-Mussaed, A Khan… - Cureus, 2020 - ncbi.nlm.nih.gov
Aims The aim of our study was to correlate liver function tests with serum ferritin levels in
multi-transfused thalassemia patients. Methods This was a descriptive cross-sectional study …

[HTML][HTML] Liver enzymes in children with beta-thalassemia major: correlation with iron overload and viral hepatitis

KM Salama, OM Ibrahim, AM Kaddah… - … journal of medical …, 2015 - ncbi.nlm.nih.gov
BACKGROUND: Beta Thalassemia is the most common chronic hemolytic anemia in Egypt
(85.1%) with an estimated carrier rate of 9-10.2%. Injury to the liver, whether acute or …

Epidemiology of HCV infection among thalassemia patients in eastern Mediterranean countries: a quantitative review of literature

SM Alavian, SV Tabatabaei… - Iranian Red Crescent …, 2010 - eprints.bmsu.ac.ir
Background: Hepatitis C infection (HCV) is the major co-morbidity in thalassemia patients;
however, literature lacks data from many EMRO counties. There is also enormous …

[PDF][PDF] Correlation of liver enzymes with serum ferritin levels in β-thalassemia major

RL Suman, A Sanadhya, P Meena… - International Journal of …, 2016 - core.ac.uk
Background: Liver is the earliest site of iron deposition in transfusion dependent β-
thalassemia major and iron induced liver injury is the common cause of morbidity. Liver …

[HTML][HTML] The etiology of hypertransaminasemia in Turkish children

F Serdaroglu, T Koca, S Dereci… - Bosnian Journal of basic …, 2016 - ncbi.nlm.nih.gov
The aim of this study was to investigate the causes of elevated levels of alanine
aminotransferase (ALT) and aspartate aminotransferase (AST) in children. We analyzed the …

[HTML][HTML] Transfusion transmitted infections in frequently transfused thalassemic children living in Fayoum Governorate, Egypt: Current prevalence and risk factors

ZT Atwa, WYA Wahed - Journal of infection and public health, 2017 - Elsevier
Regular blood transfusion therapy remains the primary treatment in thalassemia major (TM).
Transfusion-transmitted infections (TTIs) and iron overload are considered to be the major …