During almost 40 years of use, the micronucleus assay (MN) has become one of the most
popular methods to assess genotoxicity of different chemical and physical factors, including …

Micronuclei (MNi) are among the most widely studied biomarkers of DNA damage and
chromosomal instability in humans. They originate from chromosome fragments or intact …

Abstract Error-corrected Next Generation Sequencing (ecNGS) is rapidly emerging as a
valuable, highly sensitive and accurate method for detecting and characterizing mutations in …

Introduction: Genotoxicity and mutagenicity analyses have a significant role in the
identification of hazard effects of therapeutic drugs, cosmetics, agrochemicals, industrial …

Health authorities are alarmed worldwide about the increase of obesity and overweight in
the last decades which lead to adverse health effects including inflammation, cancer …

Abstract The European Commission asked EFSA to update its 2009 risk assessment on
arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the …

Micronucleus (MN) analyses in peripheral blood lymphocytes and exfoliated cells from
different organs (mouth, nose, bladder and cervix) are at present the most widely used …

The cytokinesis-block micronucleus cytome (CBMN Cyt) assay was used to evaluate the
baseline frequency of cytogenetic damage in peripheral blood lymphocytes of the general …

Abstract The lymphocyte Cytokinesis-Block Micronucleus (CBMN) assay was originally
developed for the measurement of micronuclei (MN) exclusively in binucleated (BN) cells …

Cytogenetic approaches play an essential role as a quick evaluation of the first genetic
effects after mutagenic treatment. Although labor-intensive and time-consuming, they are …