Persister Escherichia coli cells have a lower intracellular pH than susceptible cells but maintain their pH in response to antibiotic treatment
Persister and viable but non-culturable (VBNC) cells are two clonal subpopulations that can
survive multidrug exposure via a plethora of putative molecular mechanisms. Here, we …
survive multidrug exposure via a plethora of putative molecular mechanisms. Here, we …
Role of Berberine as a Potential Efflux Pump Inhibitor against MdfA from Escherichia coli: In Vitro and In Silico Studies
Y Li, X Ge - Microbiology spectrum, 2023 - Am Soc Microbiol
Infections by Gram-negative pathogens are usually difficult to manage due to the drug export
by efflux pumps. With the evolution and horizontal transfer of efflux pumps, there is an urgent …
by efflux pumps. With the evolution and horizontal transfer of efflux pumps, there is an urgent …
Single cell killing kinetics differentiate phenotypic bacterial responses to different antibacterial classes
Y Zhang, I Kepiro, MG Ryadnov… - Microbiology Spectrum, 2023 - Am Soc Microbiol
With the spread of multidrug-resistant bacteria, there has been an increasing focus on
molecular classes that have not yet yielded an antibiotic. A key capability for assessing and …
molecular classes that have not yet yielded an antibiotic. A key capability for assessing and …
Antibiotic resistant bacteria survive treatment by doubling while shrinking
Many antibiotics that are used in healthcare, farming, and aquaculture end up in
environments with different spatial structures that might promote heterogeneity in the …
environments with different spatial structures that might promote heterogeneity in the …
Phenotypic resistant single-cell characteristics under recurring ampicillin antibiotic exposure in Escherichia coli
S Kollerová, L Jouvet, J Smelková, S Zunk-Parras… - …, 2024 - journals.asm.org
Non-heritable, phenotypic drug resistance toward antibiotics challenges antibiotic therapies.
Characteristics of such phenotypic resistance have implications for the evolution of heritable …
Characteristics of such phenotypic resistance have implications for the evolution of heritable …
Eugenol works synergistically with colistin against colistin-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae isolates by enhancing membrane …
J Kong, Y Wang, Z Yao, Y Lin, Y Zhang… - Microbiology …, 2023 - Am Soc Microbiol
Colistin is a potent antibiotic for the treatment of carbapenem-resistant Gram-negative
bacteria and is considered a last-resort drug. Unfortunately, the incidence of colistin …
bacteria and is considered a last-resort drug. Unfortunately, the incidence of colistin …