The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …

Omics-based technologies have been largely adopted during this unprecedented global
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …

The SARS-CoV-2 beta coronavirus is the etiological driver of COVID-19 disease, which is
primarily characterized by shortness of breath, persistent dry cough, and fever. Because they …

Objective To define headache characteristics and evolution in relation to COVID-19 and its
inflammatory response. Methods This is a prospective study, comparing clinical data and …

COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection
to severe organ damage and death. We characterized the time-dependent progression of …

The impacts of interferon (IFN) signaling on COVID-19 pathology are multiple, with both
protective and harmful effects being documented. We report here a multiomics investigation …

Knowledge of the host response to the novel coronavirus SARS-CoV-2 remains limited,
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …

The circulating metabolome provides a snapshot of the physiological state of the organism
responding to pathogenic challenges. Here we report alterations in the plasma metabolome …

A deeper understanding of COVID‐19 on human molecular pathophysiology is urgently
needed as a foundation for the discovery of new biomarkers and therapeutic targets. Here …

The vast majority of patients (> 99%) with severe acute respiratory syndrome coronavirus 2
survive immediate infection but remain at risk for persistent and/or delayed multisystem. This …