Neuroticism is one of the most robust higher-order personality traits associated with negative
emotionality and risk of mental disorders. Many studies have investigated relationships …

Gastroesophageal reflux disease (GERD) is now one of the most common diagnoses made
in a gastroenterology practice. From a conventional pathophysiological perspective, GERD …

In this Review, after a brief historical introduction, we first provide an overview of
epidemiological studies that demonstrate an association between functional dyspepsia and …

Background: Persistent physical symptoms are common after a coronavirus disease 2019
(COVID-19) episode, but their pathophysiological mechanisms remain poorly understood. In …

This review examines the neural correlates of Gray's model (Gray and McNaughton, 2000;
McNaughton and Corr, 2004), supplemented by a fourth dimension: constraint (Carver …

Pain reduction and enhancement can be produced by means of conditioning procedures,
yet the role of awareness during the acquisition stage of classical conditioning is unknown …

Neuroticism is a robust personality trait that constitutes a risk factor for mood disorders.
Neuroimaging findings related to neuroticism have been inconsistent across studies and …

This review provides a comprehensive overview of brain imaging studies of the brain-gut
interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies …

Recent conceptualization of anxiety, depressive, and related" emotional" disorders
emphasize their similarities rather than their differences. In response, there has been a …

Background Altered pain anticipation likely contributes to disturbed central pain processing
in chronic pain conditions like irritable bowel syndrome (IBS), but the learning processes …