Social influences on neurobiology and behavior: epigenetic effects during development

JP Curley, CL Jensen, R Mashoodh… - …, 2011 - Elsevier
The quality of the social environment can have profound influences on the development and
activity of neural systems with implications for numerous behavioral and physiological …

Toward understanding how early-life social experiences alter oxytocin-and vasopressin-regulated social behaviors

AH Veenema - Hormones and behavior, 2012 - Elsevier
The early-life social environment has profound effects on brain development and
subsequent expression of social behavior. Oxytocin and vasopressin are expressed and …

Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: a …

M Sala, D Braida, D Lentini, M Busnelli, E Bulgheroni… - Biological …, 2011 - Elsevier
BACKGROUND: Oxytocin (OT) has been suggested as a treatment to improve social
behavior in autistic patients. Accordingly, the OT (Oxt−/−) and the OT receptor null mice …

Pathways relating the neurobiology of attachment to drug addiction

L Strathearn, CE Mertens, L Mayes… - Frontiers in …, 2019 - frontiersin.org
Substance use disorders constitute a significant public health problem in North America and
worldwide. Specifically, substance addictions in women during pregnancy or in the …

Developmental experiences and the oxytocin receptor system

KL Bales, AM Perkeybile - Hormones and behavior, 2012 - Elsevier
The long-term effects of developmental experiences on social behavior, and the
neuropeptide systems such as oxytocin which subserve the behavior, are still little …

Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness

JP Gouin, QQ Zhou, L Booij, M Boivin, SM Côté… - Scientific Reports, 2017 - nature.com
Recent models propose deoxyribonucleic acid methylation of key neuro-regulatory genes as
a molecular mechanism underlying the increased risk of mental disorder associated with …

Epigenetic risk factors in PTSD and depression

FJ Raabe, D Spengler - Frontiers in psychiatry, 2013 - frontiersin.org
Epidemiological and clinical studies have shown that children exposed to adverse
experiences are at increased risk for the development of depression, anxiety disorders, and …

The oxytocin system and early‐life experience‐dependent plastic changes

T Onaka, Y Takayanagi - Journal of Neuroendocrinology, 2021 - Wiley Online Library
Early‐life experience influences social and emotional behaviour in adulthood. Affiliative
tactile stimuli in early life facilitate the development of social and emotional behaviour …

Neonatal handling: an overview of the positive and negative effects

C Raineki, AB Lucion… - Developmental …, 2014 - Wiley Online Library
As one of the first rodent models designed to investigate the effects of early‐life experiences,
the neonatal handling paradigm has helped us better understand how subtle changes in the …

Early life manipulations alter learning and memory in rats

TA Kosten, JJ Kim, HJ Lee - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Much research shows that early life manipulations have enduring behavioral, neural, and
hormonal effects. However, findings of learning and memory performance vary widely …