Advances in thiosemicarbazone metal complexes as anti-lung cancer agents

XG Bai, Y Zheng, J Qi - Frontiers in Pharmacology, 2022 - frontiersin.org
The great success of cisplatin as a chemotherapeutic agent considerably increased
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …

Cuproptosis and cuproptosis-related genes: Emerging potential therapeutic targets in breast cancer

X Liu, B Luo, X Wu, Z Tang - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Breast cancer is one of the most common malignant tumors in women worldwide, and thus, it
is important to enhance its treatment efficacy [1]. Copper has emerged as a critical trace …

Medicinal applications of vanadium complexes with Schiff bases

K Hashmi, S Gupta, A Siddique, T Khan… - Journal of Trace Elements …, 2023 - Elsevier
Many transition metal complexes have been explored for their therapeutic properties after
the discovery of cisplatin. Schiff bases have an efficient complexation tendency with the …

Finding new molecular targets of two copper (II)-hydrazone complexes on triple-negative breast cancer cells using mass-spectrometry-based quantitative proteomics

LM Balsa, MR Rodriguez, V Ferraresi-Curotto… - International journal of …, 2023 - mdpi.com
Breast cancer is the most common cancer in women, with a high incidence estimated to
reach 2.3 million by 2030. Triple-Negative Breast Cancer (TNBC) is the greatest invasive …

The importance of being Casiopeina as polypharmacologycal profile (mixed chelate–copper (II) complexes and their in vitro and in vivo activities)

Z Aguilar-Jiménez, A Espinoza-Guillén… - Inorganics, 2023 - mdpi.com
In this review, we present a timeline that shows the origin of mixed chelate copper (II)
complexes, registered as Mark Title Casiopeínas®, as the first copper (II) compounds …

Novel mono-, bi-, tri-and tetra-nuclear copper complexes that inhibit tumor growth through apoptosis and anti-angiogenesis

X Wang, M Zhu, S Li, G Xu, Z Zhang, F Yang - Journal of Inorganic …, 2024 - Elsevier
To develop the next-generation metal agents for efficiently inhibiting tumor growth, a series
of novel mononuclear, binuclear and trinuclear copper (Cu) thiophene-2-formaldehyde …

Promising Dual Anticancer and Antimetastatic Action by a Cu (II) Complex Derived from Acylhydrazone on Human Osteosarcoma Models

L Santa Maria de la Parra, AIB Romo… - Inorganic …, 2024 - ACS Publications
Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …

Structural and spectroscopic studies related to vanadium chemistry and biochemistry

EJ Baran - Coordination Chemistry Reviews, 2024 - Elsevier
Different aspects of the chemistry and biochemistry of vanadium are analyzed in this review.
The preparation and characterization of oxovanadates and polyoxovanadates, including …

Recently Reported Biological Activities and Action Targets of Pt (II)-and Cu (II)-Based Complexes

CE Maciel-Flores, JA Lozano-Alvarez… - Molecules, 2024 - mdpi.com
Most diseases that affect human beings across the world are now treated with drugs of
organic origin. However, some of these are associated with side effects, toxicity, and …

Copper (II) complexes containing hydrazone and bipyridine/phenanthroline ligands for anticancer application against breast cancer cells

DP Dorairaj, P Kumar, H Rajasekaran… - Journal of Inorganic …, 2025 - Elsevier
In this work, mixed ligand Cu (II) complexes containing hydrazone and bipyridine ligands
(CB1-CB5), or hydrazone and phenanthroline ligands (CP1-CP5) have been synthesized …