A survey on methods for predicting polyadenylation sites from DNA sequences, bulk RNA-seq, and single-cell RNA-seq

W Ye, Q Lian, C Ye, X Wu - Genomics, Proteomics & …, 2023 - academic.oup.com
Alternative polyadenylation (APA) plays important roles in modulating mRNA stability,
translation, and subcellular localization, and contributes extensively to shaping eukaryotic …

The microRNA target site profile is a novel biomarker in the immunotherapy response

Y Bai, Y Li, Y Qin, X Yang, GC Tseng, S Kim… - Frontiers in …, 2023 - frontiersin.org
MicroRNAs (miRNAs) bind on the 3′ untranslated region (3′ UTR) of messenger RNAs
(mRNAs) and regulate mRNA expression in physiological and pathological conditions …

Computational methods to identify and characterize the functionality of polyadenylation isoforms

D Burri - 2023 - edoc.unibas.ch
Polyadenylation is the process by which poly (A) tails are added at the 3'end of an RNA
molecule. Alternative polyadenylation (APA) can occur when multiple poly (A) sites exist …